Comparison of standard anti-Helicobacter pylori eradication regimen with and without N Acetylcysteine ??in patients with dyspepsia
- Conditions
- Dyspepsia.Helicobacter pylori [H.pylori] as the cause of diseases classified
- Registration Number
- IRCT201201078634N1
- Lead Sponsor
- Vice chancellor for research, Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
Inclusion criteria included: All patients with gastrointestinal symptoms and dyspepsia which refer to the Gastroenterology Clinics of Al-Zahra hospital, Noor, Poursina Hakim Research Center and Ardakan hospital for endoscopy by a gastroenterologist recruited with full consent if Helicobacter pylori tests were positive (confirmed by histology, Rapid urease test or stool antigen test). Exclusion criteria included: Patients previously received eradication of Helicobacter pylori treatment? Presence of underlying disease such as cirrhosis? Renal failure? Severe cardiac disease? malignancy outside of the GI? Age less than 17 and more than 80? Simultaneous use of NSAIDs? Concomitant use of steroids? Recent gastrointestinal bleeding? pregnancy or lactation.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Helicobacter pylori eradication. Timepoint: Prior to and one month after intervention. Method of measurement: Stool antigen.
- Secondary Outcome Measures
Name Time Method Drug side effects. Timepoint: During and after drug consumption. Method of measurement: Visiting and call-chek list.;Drug tolerance. Timepoint: During drug consumption. Method of measurement: Visiting and call.