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Clinical Trials/NCT05639088
NCT05639088
Active, Not Recruiting
N/A

Improving Transition Care for Adolescents and Young Adults With Type 1 Diabetes: A Randomized Controlled Trial of SHIFT2

Virginia Commonwealth University1 site in 1 country109 target enrollmentAugust 24, 2023

Overview

Phase
N/A
Intervention
Transition preparation program
Conditions
Type 1 Diabetes
Sponsor
Virginia Commonwealth University
Enrollment
109
Locations
1
Primary Endpoint
Hemoglobin A1C (HbA1C)
Status
Active, Not Recruiting
Last Updated
16 days ago

Overview

Brief Summary

The purpose of this research study is to evaluate a transition preparation program designed for adolescents and young adults (AYAs) with type 1 diabetes (T1D). This transition program will support AYAs as they prepare to transition from pediatric to adult endocrinology medical care and will also include a caregiver. Results from this study will inform clinical recommendations regarding self-management best practices for AYAs with T1D prior to transitioning to adult medical care.

Detailed Description

Investigators will recruit adolescents and young adults ages 16-22 years with T1D and a parent/guardian. Families will participate in one of two 6-month treatments: 1) SHIFT2, engaging in monthly sessions with transition coaches providing education on diabetes management and healthcare transition, or 2) Enhanced treatment (TAU+), engaging in routine medical care and receiving monthly education (no coaches).

Registry
clinicaltrials.gov
Start Date
August 24, 2023
End Date
December 31, 2026
Last Updated
16 days ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Type 1 Diabetes diagnosis for at least 1 year (as documented in medical record)
  • 16-22 years old
  • English speaking
  • Children's Hospital of Richmond patient (Division of Pediatric Endocrinology)
  • must have a caregiver willing to participate
  • Age greater than 18 years
  • Provides care to AYA and willing to participate

Exclusion Criteria

  • Non-English speaking
  • Significant psychiatric, cognitive, medical or developmental conditions that would impair their ability to complete assessments and/or engage in diabetes self-care behaviors (e.g., malignancies, psychosis, intellectual disability
  • Hospitalization for depression, suicidal ideation or other psychiatric disorder within the past 12 months. Life time history of psychotic disorder
  • Medically-induced diabetes or diagnosis of diabetes other than type 1 diabetes.
  • Currently pregnant, pregnant within the past 6 months, currently breastfeeding or planning to become pregnant within the next 12 months.
  • Another member of the household (other than the participating parent) is a participant or staff member on this study.
  • Participation in another research study that may interfere with this study.
  • Previous participation in the SHIFT pilot study
  • Non-English speaking
  • Significant psychiatric, cognitive, developmental conditions that would impair their ability to complete assessments and/or engage in supporting the AYA with diabetes self-care behaviors (e.g., psychosis, intellectual disability)

Arms & Interventions

Group A: SHIFT2

Adolescents and young adults will engage in routine medical visits and attend 6 sessions (1x/month) focused on transition preparation and diabetes management with a transition coach and will receive bi-weekly messages during these 6-months that encourage self-management behaviors. Parents will attend 2 sessions (month 1 and 6) with a transition coach and will receive materials, complementing their child's lesson, 1x/month for months 2-5 that focus on transition their role and supporting their child's diabetes management.

Intervention: Transition preparation program

Group B: TAU+/Control

Participants will engage in routine medical visits and will receive education materials monthly (1x/month) regarding healthcare transition and diabetes management.

Intervention: Educational materials

Outcomes

Primary Outcomes

Hemoglobin A1C (HbA1C)

Time Frame: 6 months

HbA1C will be assessed using a standard assay from a routine blood draw or an at-home testing kit

Change in transition readiness

Time Frame: Baseline to 6 months

Transition readiness will be measured using the Readiness Assessment of Emerging Adults with Type 1 Diabetes Diagnosed in Youth (READDY) scale, which will be completed by AYAs.

Attendance at clinic visits

Time Frame: 6 months

Attendance at routine clinic visits will be determined from medical records and will be assessed by the number of regularly scheduled visits attended.

Change in diabetes adherence

Time Frame: Baseline to 6 months

Diabetes adherence will be assessed using the Self-Care Inventory-Revised, which will be completed by both AYA and caregivers.

Secondary Outcomes

  • Change in diabetes support(Baseline to 12 months)
  • Attendance at clinic visits(12 months)
  • HbA1C(12 months)
  • Diabetes-related events(12 months)
  • Change in transition readiness(Baseline to 12 months)
  • Change in diabetes adherence(Baseline to 12 months)
  • Change in Diabetes Distress(Baseline to 12 months)
  • Change in Self Efficacy(Baseline to 12 months)
  • Change in Quality of Life(Baseline to 12 months)

Study Sites (1)

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