NL-OMON54805招募中不适用
SINGLE DOSE ABLATIVE PREOPERATIVE RADIATION TREATMENT FOR EARLY-STAGE BREAST CANCER IN ELDERLY PATIENTS - ABLATIVE
niversitair Medisch Centrum Utrecht0 个研究点目标入组 35 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 35
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 65 至 99（—）
入选标准
- •Females at least 50 years of age, with an unifocal cT1N0M0 non-lobular breast
- •cancer on mammogram/ultrasound/MRI and sentinel node biopsy
- •Females at least 70 years of age, with an unifocal cT1-2(maximum 3 cm)N0M0
- •non-lobular breast cancer on mammogram/ultrasound/MRI and sentinel node biopsy
- •Tumor with negative Her2neu receptor and positive estogen receptor
- •Adequate communication and understanding skills of the Dutch language
排除标准
- •Legal incapacity
- •BRCA gene mutation.
- •WHO performance scale > 2.
- •Previous history of breast cancer
- •Other type of malignancy within 5 years before breast cancer diagnosis.
- •Previous history of ipsilateral breast surgery and impaired cosmetic outcome,
- •as assessed by the treating surgeon or radiation-oncologist
- •Extensive DCIS component.
- •Invasive lobular carcinoma.
- •MRI absolute contraindications as defined by the Radiology Department.
- •Multicentricity or multifocality on MRI.
- •Nodal or other organ involvement with cytological or histological
- •confirmation.
- •Treatment with neo-adjuvant chemo- and immunotherapy. .
- •Indication adjuvant chemo- and immunotherapy (endocrine treatment is
研究者
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