The Role of Exosomes in Hair Follicle Growth: A Novel Therapeutic Approach for Alopecia
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Manav Rachna Dental College
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Hair density (visually assessed)
Study Overview
Brief Summary
This is a single-center, prospective, observational clinical study designed to evaluate the therapeutic efficacy of exosome-based treatment in patients with alopecia. A total of 30 participants will receive intra-dermal injections of platelet-derived exosome-enriched plasma administered at two-week intervals for a total of three sessions. The primary objective is to assess the change in hair density visually at 3 and 6 months following the final injection. Secondary outcomes include evaluation of quality of life using patient-reported outcome measures assessed at 6 months post-treatment. The study aims to explore the regenerative potential of exosomes in promoting hair follicle growth and improving overall scalp condition in alopecia patients.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Masking
- None
Eligibility Criteria
- Ages
- 18.00 Year(s) to 70.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Diagnosed with mild to severe alopecia No history of other scalp disorders, autoimmune diseases, or active scalp infections Willing to comply with study protocols and follow-up visits.
Exclusion Criteria
- •History of chemotherapy or radiation therapy within the last year Presence of active skin or scalp infections Pregnant or breastfeeding women.
Outcomes
Primary Outcomes
Hair density (visually assessed)
Time Frame: 3 months and 6 months after last injection.
Secondary Outcomes
- Quality of life using patient-reported outcomes(At 6 months after the last injection of exosome)
Investigators
Dr Kumar Rakshak Anand
Manav Rachna Dental College