Safe Use of CPAP and PEEP During Induction of General Anesthesia
- Conditions
- General Anesthesia
- Registration Number
- NCT04271683
- Lead Sponsor
- Region Västmanland
- Brief Summary
The study compares the safety of using pressure controlled ventilation with a positive end-expiratory pressure (PEEP) during induction of general anaesthesia immediately after apnoea to a standard method starting ventilation manually without PEEP immediately after apnoea.
- Detailed Description
Using a continuous positive pressure (CPAP) during preoxygenation, followed by pressure controlled ventilation with PEEP after apnoea during induction of general anesthesia, might offer several benefits but safety issues needs more investigation. This study compares the safety of using pressure controlled with PEEP during induction of general anesthesia immediately after apnoea to a standard method starting ventilation manually without PEEP immediately after apnoea.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 70
- Normal or overweight patients scheduled for day case surgery in general anesthesia.
- American Society of Anesthesiologists functional class I-III.
- Body Mass Index 18.5-30.
- Increased risk of regurgitation of gastric content.
- Symptomatic asthma, COPD or heart failure.
- Peripheral oxygen saturation (SpO2) breathing air <94 %
- Anticipated difficult airway.
- Beard.
- Anatomical features making it difficult to keep a tight seal during maskventilation.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Number of breaths until return of CO2. 2 minutes When starting ventilation after apnea the number of breaths given until the return of CO2 is at least 1.3 kPa at a respiratory frequency of 10 per minute.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Lennart Edmark
🇸🇪Västerås, Sweden
Lennart Edmark🇸🇪Västerås, Sweden