Influence of sanitizing methods on healthcare associated infections: comparison between traditional and innovative probiotic-based approaches
Not Applicable
Completed
- Conditions
- Healthcare associated infections.Infections and Infestations
- Registration Number
- ISRCTN58986947
- Lead Sponsor
- CIAS Laboratory Centre for the Study of Physical, Chemical and Microbiological Contamination of Highly Sterile Environments, Department of Architecture
- Brief Summary
2018 Results article in https://www.ncbi.nlm.nih.gov/pubmed/30001345 results 2019 Results article in https://pubmed.ncbi.nlm.nih.gov/30881055/ (added 10/07/2023)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 18000
Inclusion Criteria
All the patients admitted to the wards of the seven hospital settings included in the study will be enrolled in the survey, without distinction of age or gender.
Exclusion Criteria
Participants that do not fulfill the inclusion criteria
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Number of total healthcare associated infections (HAIs), recorded daily in all the hospitals enrolled in the study, before and after the application of PCHS, measured as number of HAI medical records collected at the end of the pre- and post-intervention phases, corresponding respectively to 6 and 15 months starting from the beginning of the study for each hospital setting<br>2. Surface bioburden quantitation and characterization in the pre- and post-intervention phases, in all the hospitals enrolled in the study, measured monthly by both conventional microbiological (pathogen quantitation) and molecular (pathogen characterization) analyses during all the study period
- Secondary Outcome Measures
Name Time Method 1. Number of HAIs sustained by multidrug resistant (MDR) microbial strains in the pre- and post-intervention phases in all the hospitals enrolled in the study, measured at the end of each phase, namely at 6 and 15 months starting from the beginning of the study for each hospital setting<br>2. Characterization of the HAIs typology, measuring the number of HAIs transmitted by contact with contaminated surfaces at the end of the pre- and post-intervention phases in all the hospitals enrolled in the study<br>3. Identification of a parameter correlating bioburden level/type with HAIs number