A study of Heart rate Variability for Prediction of Response to Selective Serotonin Reuptake Inhibitor (SSRI) & Selective partial Agonist and Reuptake Inhibitor (SPARI) in Generalised Anxiety Disorder
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Heart Rate Variability
研究概览
简要总结
This is a prospective observational study aimed at evaluating the role of heart rate variability in predicting response to Selective Serotonin Reuptake Inhibitors and Selective Partial Agonist and Reuptake Inhibitors in patients with Generalized Anxiety Disorder. Patients will be assigned to two treatment groups based on the prescribed medication and compared with a healthy control group. Heart rate variability and anxiety severity will be assessed before and after eight weeks of treatment. The study aims to identify whether heart rate variability can serve as a predictive marker to guide personalized treatment decisions in anxiety disorders
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult patients of generalized anxiety disorder with moderate or severe anxiety based on Hamilton anxiety rating scale (HAM-A).
排除标准
- •Any physical or psychiatric co-morbidity except insomnia Patient with heart disease or taking any heart rate controlling drugs like beta blockers.
- •Pregnancy Patient with pacemaker implant.
- •Severe systemic disease, cardiopulmonary or kidney insufficiency.
结局指标
主要结局
Heart Rate Variability
时间窗: 1. Baseline | 2. After 8 weeks of treatment
次要结局
未报告次要终点
研究者
Daniyal Farooque
Jawaharlal Nehru Medical College, Aligarh