Coagubility in severe mitral regurgitation: A within-patient evaluation of coagulation status before and after Mitral Valve Transcatheter Edge-to-Edge Repair.
Recruiting
- Conditions
- Atrial fibrillation and leaking heart valve1006447710046973
- Registration Number
- NL-OMON56294
- Lead Sponsor
- Sint Antonius Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
- >= 18 years old
- Echocardiographic-proven (TTE) moderate or severe MR with a planned M-TEER
procedure
Exclusion Criteria
- Patients who are unable to provide informed consent
- Active malignancy excluding non-melanoma skin cancer
- Active liver disease (ALT, ASP, AP >3x ULN or active hepatitis A, B or C)
- Patients using, and unable to omit, nonsteroidal anti-inflammatory drugs,
corticosteroids, or hormone replacement therapy
- Known coagulopathy
- Severe anaemia requiring blood transfusion or thrombocytopenia <50 × 10^9/L
- Life expectancy <1 year
- Severe kidney failure (eGFR < 30 mL/min)
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method