Bacteriological Link Between Upper and Lower Airways in Cystic Fibrosis and Primary Ciliary Dyskinesia

Completed

• Conditions: Cystic Fibrosis; Primary Ciliary Dyskinesia

• Registration Number: NCT03494894
• Lead Sponsor: Centre Hospitalier Intercommunal Creteil

Brief Summary

Cytobacteriological examination of sputum and bacteriological sampling in the middle meatus.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-06-01
• Primary Completion: 2017-06-14
• Study First Submitted: 2018-04-04
• Study First Submitted QC: 2018-04-04
• Study First Posted: 2018-04-11
• Study Completion: 2019-02-19
• Status Verified: 2020-07
• Last Update Submitted: 2020-07-31
• Last Update Posted: 2020-08-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Patients over 6 years old
• Patients with cystic fibrosis or primary ciliary dyskinesia.
• Patients capable of performing an expectorations
• Patients having been informed of the research, having received the information note and not having opposed the research

Exclusion Criteria

• Refusal to participate in the study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Presence of bacterial colonization of the upper and lower airway	1 day

Secondary Outcome Measures

Name	Time	Method
bacteria genotype	1 day	Compare the genotype of bacteria present in both VAS and VAI.
bacteriological concordance in adult	1 day	Subgroup analysis (adult group)
bacteriological concordance in children	1 day	Subgroup analysis (group \<18 years old)
bacteriological concordance	1 day	bacteriological concordance of upper airways (VAS) and lower (VAI) between patients with cystic fibrosis and those with primary ciliary dyskinesia.

Trial Locations

Locations (1)

Centre Hospitalier Intercommunal de Créteil; 🇫🇷 Créteil, France