Predictability of the IOL Position Using an Intra-operative OCT
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 主要终点
- Correlation of intra-operative lens capsule measurements and the post-operative lens position
研究概览
简要总结
Refractive outcome after cataract surgery mainly depends on the prediction of the intraocular lens that is implanted in the eye during surgery.
Aim of this study is to measure the position of the lens capsule during surgery and to use this measurements to improve post-operative refractive outcomes.
详细描述
During the last decades the refractive outcome after cataract surgery improved significantly.
The total prediction error in IOL power calculation (and therefore in the refractive outcome) can be divided into 3 main parameters:
- Axial eye length (in mm)
- Corneal power (in dioptres)
- Estimation of post-operative anterior chamber depth (ACD) (in mm)
Since the introduction of optical biometry (IOLMaster, Carl Zeiss Meditec AG, Jena, Germany), as a reliable non-contact measurement of the axial eye length the influence of the error of axial length measurement on the refractive error decreased from over 50% (when measured with applanation ultrasound) to 36%. The mean error of corneal power measurement is approximately 22%.
These results show that the estimation of the post-operative intra-ocular lens (IOL) position and therefore the estimated anterior chamber depth (ACD) is nowadays the main source of error (35%to 42%) in IOL power calculation and therefore for the refractive outcome of the patients after cataract surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 21 and older
- •written informed consent prior to surgery
排除标准
- •Relevant other ophthalmic diseases such as: pseudoexfoliation, glaucoma, traumatic cataract, corneal scars, and other co-morbidity
- •In case of pregnancy (pregnancy test will be taken preoperatively in women of reproductive age)
结局指标
主要结局
Correlation of intra-operative lens capsule measurements and the post-operative lens position
时间窗: 3 months
Aim of this outcome parameter is to detect, if intra-operative measurements (with an optical coherence tomogrophy system) help to detect the position of the artificial lens post-operatively
次要结局
未报告次要终点
研究者
Prim. Prof. Dr. Oliver Findl, MBA
Prim. Prof. Dr., MBA
Vienna Institute for Research in Ocular Surgery