Interest of Nasal Provocation Tests for Diagnosis of House Mites Allergic Rhinitis - NPT-MAR

Centre Hospitalier Régional Metz-Thionville0 个研究点目标入组 85 人开始时间: 2019年3月26日最近更新: 2024年6月18日

适应症

试验速览

暂无简介。

•Patient over 18 years old,
•Patient with persistent mild to severe or moderate to severe intermittent rhinitis according to ARIA criteria, suspicion of allergic rhinitis to dust mites, and a positive skin test for mites and / or a positive mite specific IgE assay
•Patient having signed a free and informed consent
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 70
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 15

•Pregnant or breastfeeding women
•Patients under guardianship or curatorship
•Patients under legal protection
•Patients not affiliated to a social security scheme
•Contraindications to performing a RNPT
•o Active ENT or respiratory infections.
•o Allergy in acute phase.
•o History of anaphylaxis due to the allergen involved.
•o Unstabilized asthma and other obstructive pathologies.
•o Severe general illnesses in evolution.
•o Hypersensitivity to one of the components of the product
•o Simultaneous treatment with beta-blockers or angiotensin-converting enzyme (ACE) inhibitors,
•o Presence of an excessive degree of sensitization (e.g. history, excessive skin reactions),
•Contraindications to immunotherapy:
•o Asthma (uncontrolled)
•o Active autoimmune diseases
•o Malignant tumors
•o Pregnancy (initiation of venereal disease)

发起方

Centre Hospitalier Régional Metz-Thionville