Incorporating Avocados in Meals

Not Applicable

Completed

• Conditions: Satiety; Glycemic Index; Insulin; Gastrointestinal Peptides and Hormones

• Registration Number: NCT01271829
• Lead Sponsor: Loma Linda University

Brief Summary

The purpose of this study is to examine the effect of incorporating avocados in meals on post-ingestion glycemic index, insulin response, sensations of satiety and on appetite-related gastrointestinal peptide and hormone release. Also the effect of consuming avocado containing meals on the caloric intake of participants in subsequent eating episodes will be explored.

Each subject will participate in one intervention for one day, wait one or two weeks, come for another intervention, wait one or two weeks and come for a final intervention- three in total. Participants will be randomly assigned to one of six treatment sequences. Postprandial response to the control and two avocado-containing test meals will be assessed and compared using a 3 x 3 single blind cross-over design. The Subjects will be between 25 and 60 years old, female or male, with a BMI of 23 to 32, stable weight, no sports involvement, non-smoking and not dependent on caffeine. Thirty subjects will be recruited.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-01
• Study First Submitted: 2011-01-05
• Study First Submitted QC: 2011-01-05
• Study First Posted: 2011-01-07
• Primary Completion: 2012-09
• Study Completion: 2012-09
• Status Verified: 2014-03
• Last Update Submitted: 2014-03-17
• Last Update Posted: 2014-03-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• 23-60 years old
• BMI 23-32
• Stable weight for 6 months
• Live or work near Loma Linda University

Exclusion Criteria

• Smoker
• Heavy involvement in sports
• Dependent on caffeine

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Satiety	12 hours	The effect that consumption of avocados has on feelings of fullness and the quantity of food consumed in a subsequent eating episode

Secondary Outcome Measures

Name	Time	Method
post-ingestion glycemic index	3 hours	Blood will be drawn at 30 minutes, 60 minutes, 120 minutes and 180 minutes after consumption of a meal with or without avocados. The glycemic index will be analyzed.
insulin response	3 hours	Blood will be drawn at 30 minutes, 60 minutes, 120 minutes and 180 minutes after consumption of a meal with or without avocados. Insulin response will be analyzed.
appetite-related gastrointestinal peptide and hormone release	3 hours	Blood will be drawn at 30 minutes, 60 minutes, 120 minutes and 180 minutes after consumption of a meal with or without avocados. Gastrointestinal peptide and hormones will be analyzed.

Trial Locations

Locations (1)

Loma Linda University, Department of Nutrition; 🇺🇸 Loma Linda, California, United States