Relationship between percent of resected tissue and symptom improvement after surgical treatment of benign prostatic hyperplasia.

• Conditions: Surgical treatment of benign prostate hyperplasia; Renal and Urogenital - Other renal and urogenital disorders

• Registration Number: ACTRN12613000012774
• Lead Sponsor: Gennimatas General Hospital of Thessaloniki

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-01-07
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Male
• Target Recruitment: 100

Inclusion Criteria

1. Patients with moderate or severe LUTS (lower urinary tracts symptoms) due to BPH (benign prostatic hyperplasia) that are refractory to medical treatment

Exclusion Criteria

1. Patients with prostatic carcinoma
2. Patients with neurogenic bladder
3. Patients with Foley catheter that are going to be treated due to urinary retention

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Estimate the percent of resected tissue and collerate this with the improvement on urinary symptoms[The percent of resected tissue is going to be calculated as the resected tissue weight divided by the preoperative prostate weight x 100. The preoperative prostate weight is going to be estimated as the preoperative prostate volume x specific gravity of prostate. The prostate tissue collected at resection is going to be weighed and multiplied by 1.2 to compensate for 'shrinkage' (resected tissue weight).<br>The improvement on symptoms is going to be assessed with the questionnaire of International Prostate Symptom Score (IPSS), the extra question for quality of life (QoL), the post-void residual (PVR) urine volume and the Qmax in uroflowmetry. All these are going to be estimated preoperatively and three (3) months after the procedure.]

Secondary Outcome Measures

Name	Time	Method
If the increased amount of removed tissue influence the spontaneous detection of prostate cancer during surgical treatment of BPH(Benign Prostate Hyperplasia).[Postoperatively with the histopathologic examination. As it is known, prostate cancer more frequently is developed in the peripheral zone of prostate. So by increasing the amount of tissue resected, theoritically get closed to the peripheral zone of the prostate. ]