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Clinical Trials/NCT03612726
NCT03612726
Recruiting
Not Applicable

The Overall Survival of Patients Diagnosed With Unresectable Hepatocellular Carcinoma Under Real-life Clinical Practice in Asia Pacific Region

Humanity & Health Medical Group Limited3 sites in 3 countries5,000 target enrollmentJuly 16, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hepatocellular Carcinoma
Sponsor
Humanity & Health Medical Group Limited
Enrollment
5000
Locations
3
Primary Endpoint
Overall survival
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

Liver cancer is the fifth most common cancer and the second most frequent cause of cancer-related death globally. Hepatocellular carcinoma represents about 90% of primary liver cancers and constitutes a major global health problem. The pattern of HCC occurrence shows a significant geographical imbalance, with the highest incidence rates in East Asia (more than 50% of the cases occurring in China).

The aim of this study is to investigate the overall survival (OS) of patients diagnosed with unresectable hepatocellular carcinoma under real-world practice conditions in Asia Pacific region.

Registry
clinicaltrials.gov
Start Date
July 16, 2018
End Date
December 31, 2025
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients with a diagnosis of unresectable hepatocellular carcinoma
  • Able to comprehend and provide written informed consent in accordance with institutional guidelines.

Exclusion Criteria

  • Patients not willing to participate and/or give their written informed consent.

Outcomes

Primary Outcomes

Overall survival

Time Frame: Up to 5 years

Overall survival (OS) is defined as the time (days) from the date of unresectable HCC diagnosis to the date of death, due to any reason. Patients alive or lost to follow-up at the time of analysis will be censored at their last date of follow-up

Secondary Outcomes

  • Progression-free survival (PFS)(Up to 5 years)
  • Time to progression (TTP)(Up to 5 years)
  • Frequency and Severity of Adverse Events(Up to 5 years)
  • Duration of treatment(Up to 5 years)

Study Sites (3)

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