Skip to main content
Clinical Trials/NCT06674785
NCT06674785
Recruiting
Not Applicable

Effects of Extracorporeal Shock Wave Therapy on Shoulder Internal Rotator Spasticity in Post-Stroke Patients: A Randomized Controlled Trial

National Taiwan University Hospital1 site in 1 country40 target enrollmentJuly 23, 2025

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
National Taiwan University Hospital
Enrollment
40
Locations
1
Primary Endpoint
passive range of motion for the shoulder joints
Status
Recruiting
Last Updated
9 months ago

Overview

Brief Summary

Extracorporeal shock wave therapy (ESWT) has shown potential in reducing post-stroke limb spasticity. This study aims to evaluate the efficacy of focused ESWT on shoulder internal rotator spasticity in post-stroke patients.

Detailed Description

This study aimed to evaluate the effects of focused extracorporeal shock wave therapy (ESWT) on shoulder internal rotator spasticity in stroke patients. Participants were randomized into two groups: an experimental group receiving targeted ESWT on specific shoulder internal rotators, and a control group receiving placebo treatments mimicking the shockwave therapy, with treatments administered twice weekly over two weeks for a total of four sessions. The efficacy of the treatment was measured using a comprehensive set of assessment tools, including range of motion, pain levels, spasticity scales, functional assessments, as well as measures of daily living activities, and ultrasound strain elastography. The outcomes were evaluated at multiple points in time: before treatment, and 1, 4, 12, and 24 weeks after the therapy concluded, to assess both immediate and sustained effects of the treatment on shoulder function and spasticity in stroke survivors.

Registry
clinicaltrials.gov
Start Date
July 23, 2025
End Date
December 31, 2027
Last Updated
9 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients aged 18 years or older with unilateral cerebral stroke.
  • Restricted passive external rotation of the spastic shoulder by more than 20 degrees.
  • A Modified Ashworth Scale score of 1 or higher for shoulder internal rotator spasticity.
  • Stable medical condition and vital signs.
  • Clear consciousness, able to follow instructions.

Exclusion Criteria

  • History of two or more strokes, traumatic brain injury, brain tumors, or other cerebral disorders.
  • Coexisting central nervous system disorders (e.g., spinal cord injury, Parkinson's disease) or other musculoskeletal conditions affecting muscle tone assessment.
  • Ineligibility for shock wave intervention due to malignancies, coagulation disorders, localized infections, or presence of a pacemaker.
  • Prior shock wave intervention or botulinum toxin injection for post-stroke spasticity within the past three months.
  • Inability to participate in interventions or functional assessments due to cognitive, consciousness, or language impairments.

Outcomes

Primary Outcomes

passive range of motion for the shoulder joints

Time Frame: pre-treatment; 1, 4, 12, and 24 weeks post-treatment

the extent to which a joint can be moved without the patient actively participating in the movement

shoulder strength

Time Frame: pre-treatment; 1, 4, 12, and 24 weeks post-treatment

the muscle power generated by the shoulder muscles, quantified using the Medical Research Council (MRC) scale, which grades muscle strength from 0 (no visible contraction) to 5 (normal strength against full resistance)

Visual Analogue Scale (VAS)

Time Frame: pre-treatment; 1, 4, 12, and 24 weeks post-treatment

individuals rate their pain from 0 to 10, where 0 represents 'no pain' and 10 signifies 'the worst pain imaginable

modified Ashworth scale (MAS)

Time Frame: pre-treatment; 1, 4, 12, and 24 weeks post-treatment

Evaluate spasticity in individuals with neurological conditions. The scale ranges from 0, indicating no increase in muscle tone, to 4, which represents severe spasticity with affected parts rigid in flexion or extension.

Secondary Outcomes

  • Fugl-Meyer Assessment for the Upper Extremity (FMA-UE)(pre-treatment; 1, 4, 12, and 24 weeks post-treatment)
  • Action Research Arm Test (ARAT)(pre-treatment; 1, 4, 12, and 24 weeks post-treatment)
  • Barthel index(pre-treatment; 1, 4, 12, and 24 weeks post-treatment)
  • Wolf Motor Function Test(pre-treatment; 1, 4, 12, and 24 weeks post-treatment)
  • ultrasound assessment(pre-treatment; 1, 4, 12, and 24 weeks post-treatment)

Study Sites (1)

Loading locations...

Similar Trials