NCT01295411UnknownNot Applicable
Morphological, Structural and Functional Neural Substrates of Quality of Life in Schizophrenia
Assistance Publique Hopitaux De Marseille2 sites in 1 country100 target enrollmentStarted: January 2011Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 100
- Locations
- 2
- Primary Endpoint
- to study the relationships between quality of life and the morphologic, structural and functional substrates in schizophrenia
Study Overview
Brief Summary
The aim of the investigators analysis is to identify the neural correlates of quality of life scores in schizophrenia. For this, the investigators will constitute group of patients according to their quality of life scores and the investigators will analyze their differences in patterns of brain structures and activations.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 40 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •diagnosis of schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria (American Psychiatric Association(APA), 1994),
- •age over 18 years,
- •informed consent to participate in the studies
- •French as native language
Exclusion Criteria
- •diagnosis other than schizophrenia on Axis I of DSM-IV,
- •decompensated organic disease and mental retardation
Outcomes
Primary Outcomes
to study the relationships between quality of life and the morphologic, structural and functional substrates in schizophrenia
Time Frame: 36 months
Secondary Outcomes
- to determine whether quality of life is correlated with brain modifications using functional Magnetic Resonance Imaging(36 months)
Investigators
Study Sites (2)
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