NCT00223470已完成不适用
Cytokine Regulation of Periradicular Pain in Humans
The University of Texas Health Science Center at San Antonio1 个研究点 分布在 1 个国家目标入组 9 人开始时间: 2002年10月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9
- 试验地点
- 1
研究概览
简要总结
This clinical trial evaluates the role of cytokines in patients needing root canal treatment with diagnosis of necrotic pulp and chronic apical periodontitis
详细描述
This study evaluates whether periradicular exudate concentrations of cytokines differ in patients experiencing pain and mechanical allodynia due to pulpal necrosis with an acute exacerbation of a chronic apical periodontitis, as compared to patients with pulpal necrosis with chronic apical periodontitis, but no pain or mechanical allodynia
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 16 Years 至 60 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient must be at least 16 years of age.
- •Clinical indication for Non-Surgical Root Canal Therapy (NSRCT).
- •1st or 2nd maxillary or mandibular molar
- •Diagnosis must be Chronic Apical Periodontitis (CAP) with or without symptoms.
- •Intact, mature apices.
- •ASA I or II
排除标准
- •Failure to meet any of the above
- •Previous NSRCT
- •Previous pulpotomy or pulpectomy
- •Suppurative apical periodontitis
- •Patients taking medications which can affect their pain rating or medications which effect their immune system ( such as glucocorticoids)
研究者
研究点 (1)
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