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Clinical Trials/NCT05117411
NCT05117411
Completed
Not Applicable

Peripapillary Vascular Density in the Pathogenesis of Pseudophakic Cystoid Edema

Federico II University0 sites25 target enrollmentJanuary 1, 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pseudophakic Cystoid Macular Edema
Sponsor
Federico II University
Enrollment
25
Primary Endpoint
OCTA and pseudophakic cystoid macular oedema
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

This study evaluates the retinal vascular features in macula and papillary regions in patients affected by pseudophakic cystoid edema using optical coherence tomography angiography

Detailed Description

Pseudophakic cystoid edema represents one of the most common causes of poor visual outcome following cataratta surgery. It is still source of debate the pathogenesis of Pseudophakic cystoid edema. Optical coherence tomography angiography represents a novel and non-invasive diagnostic technique that allows a detailed analysis of retinal vascular features. The study evaluates retrospectively the changes in optical coherence tomography angiography parameters at baseline and after three monthly after surgery.

Registry
clinicaltrials.gov
Start Date
January 1, 2016
End Date
December 30, 2020
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Federico II University
Responsible Party
Principal Investigator
Principal Investigator

Gilda Cennamo

Principal Investigator

Federico II University

Eligibility Criteria

Inclusion Criteria

  • age older than 60 years
  • diagnosis of pseudophakic cystoid macular oedema
  • treatment-naïve for pseudophakic cystoid macular oedema
  • absence of other ocular diseases, responsible for macular edema (retinal vein occlusion, diabetic retinopathy, age-related macular degeneration)

Exclusion Criteria

  • age younger than 60 years
  • No diagnosis of pseudophakic cystoid macular oedema
  • previous treatment for pseudophakic cystoid macular oedema
  • presence of other ocular diseases, responsible for macular edema (retinal vein occlusion, diabetic retinopathy, age-related macular degeneration)

Outcomes

Primary Outcomes

OCTA and pseudophakic cystoid macular oedema

Time Frame: 3 months

The parameters analyzed by OCTA three months after surgery are: Vessel density (%) of superficial capillary plexus, deep capillary plexus, coriocapillary plexus in macular region Vessel density (%) of radial peripapillary capillary plexus in papilllary region

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