Comparison of recovery of mental and motor skills in patients receving either intravenous propofol or dexmedetomidine infusions as part of balanced general anaesthesia:A prospective randomized single-blind study
Phase 4
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/06/034393
- Lead Sponsor
- nil
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients with American Society of Anaesthesiologists physical status I, II, III aged 18 to 65 years.
2.Patients who are scheduled for surgeries under general anaesthesia.
3.Minimum duration of surgery lasting more than 120 minutes.
Exclusion Criteria
1.Patients unwilling to participate in the study.
2.Patients who are unable to give informed consent.
3.BMI >30kg/m2.
4.Patients with known history of psychiatric illness, chronic drug or alcohol abuse.
5.Patients with known hypersensitivity to drugs used.
6.Pregnant and lactating women.
Patients on concurrent sedative medications.
7.Patients who are unable to attempt or perform the DSST test.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method compare the psychomotor recovery of patients receiving iv dexmedetomidine versus iv propofol infusion with Digit Symbol Substitution Test(DSST)[Annexure1] postoperativelyTimepoint: 15 min, 30 min , 60 min , 90 min , 120 min
- Secondary Outcome Measures
Name Time Method i.To note the number of additional bolus doses of fentanyl and propofol given intraoperatively. <br/ ><br> ii.To note the total amount of propofol and fentanyl consumed intraoperatively. <br/ ><br> iii.To compare the time taken from stoppage of infusion to opening of eyes before administration of reversal agent. <br/ ><br> iv. To assess the sedation of patients with Ramsay Sedation Assessment Scale. <br/ ><br>Timepoint: 15 min, 30 min, 60 min , 90 min, 120 min