Comparison of Levobupivacaine and Ropivacaine in Patients Undergoing Forearm Orthopaedic Surgeries under Brachial Plexus Block
- Conditions
- Diseases of the musculoskeletal system and connective tissue,
- Registration Number
- CTRI/2019/04/018608
- Lead Sponsor
- Department of Anaesthesiology
- Brief Summary
A Prospective Randomized Study to compare Levobupivacaine and Ropivacaine in Patients Undergoing Forearm Orthopaedic Surgeries under Ultra Sound Guided Supraclavicular Brachial Plexus Block.
The patients will be randomly divided into two groups using “chit and box†method. a) Group I (L): Patient proposed to undergo upper limb surgery under Supraclavicular brachial plexus block using 30ml of 0.5% Levobupivacaine. b) Group II (R): Patients proposed to undergo upper limb surgery under Supraclavicular brachial plexus block using 30ml of 0.5% Ropivacaine.
The patients will be placed in a supine position, with the head turned away and the ipsilateral arm adducted. Skin will be prepared with 10% povidone-iodine solution. All the patients will receive ultra sound(Sono site M-Turbo, Sono site , Inc., Bothwell , MO,USA)guided probe(frequency 10-15 MHz, covered with a sterile dressing) to sub fascial intracluster supraclavicular brachial plexus block which was performed by the anesthesiologist.
The needle will be removed and firm digital pressure with gauze piece will be held at the site for 5min to assist in proximal spread of the anesthetic solution.
Sensory and motor block will be evaluated preoperatively to determine a baseline and every 5 min for 30 min or until onset of blockade will be noted and thereafter every 60 min. Sensory block will be assessed by the pinprick method (22G hypodermic needle).Hemodynamic parameters and vitals (Blood pressure, Heart rate, Respiratory rate and Oxygen saturation) will be also monitored during the procedure. REFRENCES:
[1] Shantanu B, Kulkarni, Pimpare M, Balasaheb T, Govardhane. Comparison of levobupivacaine with Ropivacaine for supraclavicular brachial plexus block.Int J Res Med Sci. 2016;4:3789-96. [2] Kumar S, Palaria U, Sinha AK, Punera DC, Pandey V. Comparative evaluation of ropivacaine and ropivacaine with dexamethasone in supraclavicular brachial plexus block for postoperative analgesia. Anesth Essays Res. 2014;8:202–08.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 56
American Society of Anesthesiologists (ASA) grade I & II patients Age group 18- 60 years Patients with BMI 18.5-22.9 kg/m2 Elective cases.
- Infection at the end site of injection Neuromuscular disorder Patients with pre-existing diseases, cardiovascular or cerebrovascular diseases, Severely altered mental status.
- Patient converted to general anesthesia intra-operatively.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Study the effects of Levobupivacaine versus Ropivacaine in patients undergoing forearm orthopedic surgeries under ultra sound guided supraclavicular brachial plexus block. 18 months
- Secondary Outcome Measures
Name Time Method Sensory block, Motor block , Haemodynamic parameters, and side effects. 18 months
Trial Locations
- Locations (1)
Teerthanker Mahaveer Medical college and research center
🇮🇳Moradabad, UTTAR PRADESH, India
Teerthanker Mahaveer Medical college and research center🇮🇳Moradabad, UTTAR PRADESH, IndiaDr Razi ShahidPrincipal investigator9335959296razishahid7866@gmail.com