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Comparison of Levobupivacaine and Ropivacaine in Patients Undergoing Forearm Orthopaedic Surgeries under Brachial Plexus Block

Phase 4
Completed
Conditions
Diseases of the musculoskeletal system and connective tissue,
Registration Number
CTRI/2019/04/018608
Lead Sponsor
Department of Anaesthesiology
Brief Summary

A Prospective Randomized Study to compare Levobupivacaine and Ropivacaine in Patients Undergoing Forearm Orthopaedic Surgeries under Ultra Sound Guided Supraclavicular Brachial Plexus Block.

The patients will be randomly divided into two groups using “chit and box†method. a) Group I (L): Patient proposed to undergo upper limb surgery under Supraclavicular brachial plexus block using 30ml of 0.5% Levobupivacaine. b) Group II (R): Patients proposed to undergo upper limb surgery under Supraclavicular  brachial plexus block using 30ml of 0.5% Ropivacaine.

The patients will be placed in a supine position, with the head turned away and the ipsilateral arm adducted. Skin will be prepared with 10% povidone-iodine solution. All the patients will receive ultra sound(Sono site M-Turbo, Sono site , Inc., Bothwell , MO,USA)guided probe(frequency 10-15 MHz, covered with a sterile dressing)  to sub fascial intracluster supraclavicular brachial plexus block which was performed by  the anesthesiologist.

The needle will be removed and firm digital pressure with gauze piece will be held at the site for 5min to assist in proximal spread of the anesthetic solution.

Sensory and motor block will be evaluated preoperatively to determine a baseline and every 5 min for 30 min or until onset of blockade will be noted and thereafter every 60 min. Sensory block will be assessed by the pinprick method (22G hypodermic needle).Hemodynamic parameters and vitals (Blood pressure, Heart rate, Respiratory rate and Oxygen saturation) will be also monitored during the procedure. REFRENCES:

[1] Shantanu B, Kulkarni, Pimpare M, Balasaheb T, Govardhane. Comparison of levobupivacaine with Ropivacaine for supraclavicular brachial plexus block.Int J Res Med Sci. 2016;4:3789-96. [2] Kumar S, Palaria U, Sinha AK, Punera DC, Pandey V. Comparative evaluation of ropivacaine and ropivacaine with dexamethasone in supraclavicular brachial plexus block for postoperative analgesia. Anesth Essays Res. 2014;8:202–08.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
56
Inclusion Criteria

American Society of Anesthesiologists (ASA) grade I & II patients Age group 18- 60 years Patients with BMI 18.5-22.9 kg/m2 Elective cases.

Exclusion Criteria
  • Infection at the end site of injection Neuromuscular disorder Patients with pre-existing diseases, cardiovascular or cerebrovascular diseases, Severely altered mental status.
  • Patient converted to general anesthesia intra-operatively.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Study the effects of Levobupivacaine versus Ropivacaine in patients undergoing forearm orthopedic surgeries under ultra sound guided supraclavicular brachial plexus block.18 months
Secondary Outcome Measures
NameTimeMethod
Sensory block, Motor block , Haemodynamic parameters, and side effects.18 months

Trial Locations

Locations (1)

Teerthanker Mahaveer Medical college and research center

🇮🇳

Moradabad, UTTAR PRADESH, India

Teerthanker Mahaveer Medical college and research center
🇮🇳Moradabad, UTTAR PRADESH, India
Dr Razi Shahid
Principal investigator
9335959296
razishahid7866@gmail.com

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