Clinical Evaluation of Dimethyl Sulfoxide Wet Bonding Technique

Not Applicable

Not yet recruiting

• Conditions: Dimethyl Sulfoxide
• Interventions: Other: Universal single bond adhesive; Other: DMSO

• Registration Number: NCT06635382
• Lead Sponsor: Manipal University College Malaysia

Brief Summary

Dimethyl sulfoxide (DMSO) wet bonding has shown promising results in several in vitro studies. However, there are a lack of clinical trials which prove the advantages of this technique. The aim of the study is to clinically assess the effect of DMSO wet bonding on composite restoration in non carious cervical lesions.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-09-02
• Status Verified: 2024-10
• Study First Submitted QC: 2024-10-08
• Last Update Submitted: 2024-10-08
• Study First Posted: 2024-10-10
• Last Update Posted: 2024-10-10
• Study Start: 2024-10-20
• Primary Completion: 2025-02-01
• Study Completion: 2025-04-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

• Two similar non carious cervical lesions (NCCLs) on the facial/labial surfaces of premolars.
• NCCLs of score 1-3 on the Smith and Knight tooth wear index.
• Favorable occlusion and teeth are in normal contact.

Exclusion Criteria

• NCCLs on the lingual surface.
• Medically compromised individuals.
• Periodontally compromised teeth.
• Bruxism and visible wear facets in the posterior dentition.
• Fractured or visibly cracked premolars and canines.
• Known allergies to resin-based restorative materials.
• Presently undergoing orthodontic treatment.
• Abutment teeth for fixed or removable prostheses.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Universal single bond adhesive	Universal single bond adhesive	-
DMSO application before Universal single bond adhesive	Universal single bond adhesive	-
DMSO application before Universal single bond adhesive	DMSO	-

Primary Outcome Measures

Name	Time	Method
Fracture of material	From treatment to 3-6 months follow up	Different fracture patterns and retention failures may occur in relation to the type of restoration: cracks, chipping/ delamination, bulk fractures, or incomplete and complete loss of retention. Assessed by Visual examination and short air drying. Criteria set from Clinically excellent/very good(sufficient) (Score 1) to Clinically poor (entirely insufficient)(Score 5)
Marginal adaptation	From treatment to 3-6 months follow up	There are different interfaces between the dental hard tissue, restorative material, and adhesive and/or luting resin/cement layer. Each interface can degrade and potentially alter marginal adaptation. In clinical practice, it is impossible to distinguish failures between the different interfaces. Therefore, only the marginal adaptation as such can be assessed by visual examination and short air drying.; Scores given depending upon the quality of restoration from Clinically excellent/very good (sufficient) (Score 1) to Clinically poor (entirely insufficient) (Score 5)