Effect of tretinoin nano lipid on acne
Phase 2
- Conditions
- acne.Acne vulgaris
- Registration Number
- IRCT20161207031288N2
- Lead Sponsor
- Jarfandishan-e Navid-e Salamat (Janus) knowledge-based company
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
1.Aged between 12 to 40 years
2.10 -50 acne lesions
3.No change in diet and life style during the study
4.Signed informed consent voluntarily and knowingly
Exclusion Criteria
Long-time exposure to UV radiation
History of sensitivity to topical anti acne drug therapy
Use of topical anti acne drug therapy including AHA, BHA, benzyl peroxide, vitamin A, retin-A, antibiotics within one month prior to the study
Pregnancy / breastfeeding
History of systemic antibiotics for acne treatment within one month prior to the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Modified acne severity index. Timepoint: Beforeintervention, one mouthlater ,two mounth after intervention. Method of measurement: MPA580.
- Secondary Outcome Measures
Name Time Method Skin PH. Timepoint: Before and after 4 and 8 weeks. Method of measurement: MPA580.;Skin sebum. Timepoint: Before and after 4 and 8 weeks. Method of measurement: MPA580.;Skin melanin and erythem. Timepoint: Before and after 4 and 8 weeks. Method of measurement: MPA580.;Transepidermal water loss. Timepoint: Before and after 4 and 8 weeks. Method of measurement: MPA580.;Hydration. Timepoint: Before and after 4 and 8 weeks. Method of measurement: MPA580.;Size and value of acne. Timepoint: Before and after 4 and 8 weeks. Method of measurement: Visiopor.