Prediction of Hemodynamic Reactivity During Suspension Laryngoscopy Using Analgesia/Nociception Index (ANI)

Completed

• Conditions: Anesthesia

• Registration Number: NCT01796210
• Lead Sponsor: Emmanuel Boselli

Brief Summary

The aim of this study is to evaluate the performance of Analgesia/Nociception Index for the prediction of hemodynamic reactivity in adult patients undergoing suspension laryngoscopy on general anesthesia.

Detailed Description

Measurement of analgesia/nociception index at different time points during procedure and assessment of analgesia/nociception index to predict hemodynamic reactivity by building receiver observer's characteristic curve.

Study Timeline

• Study Start: 2012-10
• Study First Submitted: 2013-02-18
• Study First Submitted QC: 2013-02-19
• Study First Posted: 2013-02-21
• Primary Completion: 2013-05
• Study Completion: 2013-05
• Status Verified: 2013-06
• Last Update Submitted: 2013-06-06
• Last Update Posted: 2013-06-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Age 18-75 years
• Suspension laryngoscopy for diagnostic or therapeutic purposes
• Total intravenous anesthesia using propofol and remifentanil

Exclusion Criteria

• age <18 yrs or >75 yrs
• arrythmia
• administration of anticholinergic drugs or neuromuscular blockade reversal in the 20 previous minutes
• psychiatric diseases
• autonomic nervous system disorders (epilepsy)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in heart rate and/or systolic blood pressure by more than 20% within 5 minutes	Before induction of anesthesia, 1 min after beginning of procedure, at steady-state anesthesia during procedure (an expected average of 10 min) and at arousal from general anesthesia in the end of procedure (an expected average of 20 min)

Trial Locations

Locations (1)

Hôpital Édouard Herriot, HCL; 🇫🇷 Lyon, Rhône, France