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Clinical Trials/NCT02849054
NCT02849054
Unknown
Not Applicable

Optimisation of Neonatal Ventilation: Congenital Diaphragmatic Hernia - Determining the Appropriate Level of Volume Guarantee

King's College London1 site in 1 country18 target enrollmentJune 2016
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ConditionsCongenital Diaphragmatic Hernia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Congenital Diaphragmatic Hernia
Sponsor
King's College London
Enrollment
18
Locations
1
Primary Endpoint
Change in Pressure Time Product of the diaphragm (PTPdi) at different levels of targetted tidal volume
Last Updated
7 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

To determine the appropriate volume (size) of ventilator breath during volume-targetted ventilation for infants born with congenital diaphragmatic hernia.

Registry
clinicaltrials.gov
Start Date
June 2016
End Date
December 2021
Last Updated
7 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •Congenital diaphragmatic hernia - post-operative Mechanically ventilated Born at \>34/40

Exclusion Criteria

  • •neuromuscular blockade contraindications to NG/OG tube insertion

Outcomes

Primary Outcomes

Change in Pressure Time Product of the diaphragm (PTPdi) at different levels of targetted tidal volume

Time Frame: 3 hours

PTPdi will be measured at each level of tidal volume. The outcome measure is the change in PTPdi.

Study Sites (1)

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