Bipolar Versus Monopolar Resection of Benign Prostate Hyperplasia: A Comparison of the Effects on Plasma Electrolytes, Osmolarity and Hemoglobin
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Hyponatremia
- Sponsor
- Istanbul University
- Enrollment
- 53
- Locations
- 1
- Primary Endpoint
- Serum sodium level
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Aim of this prospective clinical study was to compare two different surgical techniques and used solutions on serum electrolytes, bleeding and Transurethral Resection of Prostate (TURP) syndrome undergoing TURP.
Fifty-three patients scheduled for elective TURP were enrolled in this prospective clinical study. Patients were included one of two groups (Group Monopolar and Group Bipolar).
Detailed Description
Background and Purpose: Aim of this prospective clinical study was to compare two different surgical techniques and used solutions on serum electrolytes, bleeding and Transurethral Resection of Prostate (TURP) syndrome undergoing TURP. Methods: Fifty-three patients scheduled for elective TURP were enrolled in this prospective clinical study. Patients were divided into two groups. Patients in Group M (Monopolar) (n=25) were used monopolar resectoscope (Karl Storz, Tottling, Germany) and 5% mannitol as irrigating solution. Patients in Group B (Bipolar) (n=25) were used bipolar resectoscope TURis (OLYMPUS, Tokyo, Japan) and isotonic saline as irrigating solution. Patients who received spinal anaesthesia were given 2.5-3 ml 0.5% hyperbaric bupivacain intrathecally and others were given general anaesthesia. Patients demographics, prostate volumes, hemodynamic parameters, volumes of irrigation and IV solutions were recorded. Blood samples were collected preoperatively (control), 45 minutes after the induction (2nd Measurement) and 1 hour after the end of the operation for analyzing serum electrolytes, osmolarity, hemoglobin values.
Investigators
Meltem Savran Karadeniz
Attending Anesthesiologist
Istanbul University
Eligibility Criteria
Inclusion Criteria
- •Men were older than 50 years
- •Men suffered from symptomatic benign prostatic hyperplasia.
Exclusion Criteria
- •History of severe heart failure
- •History of respiratory failure
- •History of bleeding diathesis
Outcomes
Primary Outcomes
Serum sodium level
Time Frame: 0-3 hours
Sodium level (meq /L)
Secondary Outcomes
- Serum osmolarity(0-3 hours)
- Serum hemoglobin level(0-3 hours)
- Serum potassium levels(0-3 hours)