Evaluation of Platelet Function in Pregnancy With Multiple Electrode Aggregometry
- Conditions
- Platelet FunctionPregnancy
- Registration Number
- NCT01881698
- Lead Sponsor
- Medical University of Vienna
- Brief Summary
Establishment of a range of normal values in pregnancy with the Multiple Electrode Aggregometry (Multiplate@) device, a device that allows measurement of not only platelet count but platelet function. This has not been studied in ths special patient group. Results from this trial will be used as a basis for further investigation of abnormal platelet function in pregnancy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 200
- pregnancy
- Rejection of informed consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change of platelet function 4x, as specified below Measurement of change of platelet function by the Multiplate® device. First measurement (baseline measurement) at enrollment into the trial. Second measurement during government-mandated gynaecological evaluation, around the 20th week of pregnancy.
Third measurement immediately prior to delivery. Last measurement one week after delivery. 2nd, 3rd and 4th measurement for assessment of change from baseline.
- Secondary Outcome Measures
Name Time Method Platelet-associated complications 4x, as specified below (baseline, 20th week) Record of bleeding events, preeclampsia, HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome.
Time points: at every assessment of primary outcome measure, as described above.
Trial Locations
- Locations (1)
Universitätsklinik für Frauenheilkunde, Allgemeines Krankenhaus der Stadt Wien
🇦🇹Vienna, Austria