Fractures of the Humeral Shaft With Primary Radial Nerve Palsy: Do Injury Mechanism, Fracture Type, or Treatment Influence Nerve Recovery: A Retrospective Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 主要终点
- Changes in nerve recovery; Nerve recovery after humeral shaft fracture and surgical treatment, Functional assessment
研究概览
简要总结
This study addresses the question if patients with fractures of the humeral shaft and primary radial nerve palsy gain nerve recovery.
Additionally the influence of injury mechanism, fracture type, and treatment modality on nerve recovery should be evaluated.
详细描述
Adult fractures of the humeral shaft account for approximately 3% of all fractures; most can be treated nonoperatively. Due to the anatomy of the radial nerve and the entrapment between fragments in spiral fractures of the humerus, these injuries are associated with primary radial nerve palsy in up to 18%.
Therefore, the purpose of this study was to assess the influence of injury mechanism, fracture type, and type of surgical treatment on time to onset of nerve recovery and time to full nerve recovery in patients with humeral shaft fractures and concomitant primary radial nerve palsy.
A retrospective analysis of prospectively collected data for all patients treated with humeral shaft fracture and primary radial nerve palsy at an academic Level-I trauma center was performed. Between 1994 and 2013 a total of 615 patients with traumatic humeral shaft fractures were treated at the department. The dataset was examined for completeness and accuracy. Patients with an incomplete dataset, those with a pathologic or periprosthetic fracture, patients with non-surgical treatment, or who were younger than 18 years of age were excluded from this series. According to these criteria, a total of 50 patients with a humeral shaft fracture and primary radial nerve underwent surgical treatment
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients treated with humeral shaft fracture and primary radial nerve palsy between 1994 and 2013 at the Department of Trauma Surgery, Medical University of Vienna
- •surgical treatment
- •complete data sets
- •minimum 18 years of age
排除标准
- •Patients with an incomplete dataset
- •those with a pathologic or periprosthetic fracture
- •patients with non-surgical treatment
- •or who were younger than 18 years of age
结局指标
主要结局
Changes in nerve recovery; Nerve recovery after humeral shaft fracture and surgical treatment, Functional assessment
时间窗: through study completion, from date of inclusion till first documented changes in nerve recovery, from date of admission assessed up to 36 months
Functional assessment was routinely performed at all follow up visits including a clinical evaluation and muscle strength (M0-M5) with a manual muscle test that was graded according to Daniels and Worthingham.
次要结局
- Nerve conduction studies (NCV) were performed routinely at two weeks following onset of radial nerve palsy and after 4 months in case of delayed recovery.(2 weeks, 4 months)
- Radiographic examination via X-ray in two planes(3, 6 and 12 months after trauma)
研究者
Thomas Tiefenboeck, M.D., MSc
Principal Investigator
Medical University of Vienna