Comparison Of Efficacy Of Dentifrice Containing 5% Fluorocalcium Phosphosilicate With Dentifrice Containing Potassium Nitrate And Placebo On Dentinal Hypersensitivity: A Triple Masked Randomized Controlled Clinical Trial
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Dentinal Hypersensitivity
- Sponsor
- Government Dental College and Research Institute, Bangalore
- Enrollment
- 120
- Locations
- 1
- Primary Endpoint
- Visual Analogue Scale score for Dentinal Hypersensitivity
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
Aim of this study was to assess and compare the efficacy of a dentifrice containing 5% fluoro calcium phosphosilicate and dentifrice containing potassium nitrate on Dentinal Hypersensitivity (DH) compared to a placebo over a period of 6 weeks.
Detailed Description
A total of 120 subjects were divided into 3 groups randomly. Group 1 was given the dentifrice containing 5% fluoro calcium phosphosilicate ,Group 2 was given the dentifrice containing potassium nitrate and group 3 was given placebo. Sensitivity scores (VAS score) were recorded at baseline, 2 weeks, 6 weeks.
Investigators
Dr. A R Pradeep
Head and Professor
Government Dental College and Research Institute, Bangalore
Eligibility Criteria
Inclusion Criteria
- •The volunteers selected at baseline were in good general health and should have at least 20 natural permanent teeth and history of hypersensitivity to hot, cold, sour stimuli on at least two teeth with a VAS score of ≥4.
Exclusion Criteria
- •Patients with active cervical caries or deep abrasion requiring cervical filling, chipped teeth or fractured cusps, tender tooth in same quadrant as the hypersensitive teeth, Subjects using any type of desensitizing paste or desensitizing therapy for last 6 months, Pregnant/ lactating women or subjects with history of chronic use of anti-inflammatory and analgesic medications were excluded.
Outcomes
Primary Outcomes
Visual Analogue Scale score for Dentinal Hypersensitivity
Time Frame: Change in VAS score from Baseline to 12 weeks
Based on a 10-cm VAS score which was used to measure tooth sensitivity, a pain-free response was allotted a score of zero whereas a score of 10 was given to subjects with excruciating pain or discomfort.