NCT06476080尚未招募不适用
Ultrasound Guided Serratus Anterior Versus Erector Spinae Block in Pain Alleviation in Acute Herpes Zoster: A Prospective Comparative Study
Minia University0 个研究点目标入组 120 人开始时间: 2024年7月5日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
- 主要终点
- pain score
研究概览
简要总结
Acute herpes zoster pain is very severe . Conventional analgesics may be of no value. Regional blocks may play a role
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult population between 30 and 75 years old.
- •Unilateral painful thoracic herpetic eruption of less than one week duration.
- •VAS more than or equal 4, persistent pain in spite of proper antiviral and analgesic therapy, (800 mg oral acyclovir, 5 times per day, for one week), pregabalin 300 mg per day, acetaminophen 1000 mg per day, topical calamine lotion).
排除标准
- •Diabetic patients.
- •Painful herpetic eruptive vesicles more than one week.
- •Abdominal herpetic eruptions.
- •Non-compliant on anti-viral (bulbar palsy for example).
- •Co-malignancy or radiotherapy.
- •Steroid therapy > 5 mg prednisolone or its equivalent.
- •Infections or hematoma at site of injection.
- •Coagulopathy (chronic kidney or liver disease, clopidogrel use).
结局指标
主要结局
pain score
时间窗: immediate after injection, 1 week, 1, 3 months
Visual analogue scale from 0 to 10. 0= NO pain, 1-3=mild tolerable pain, 4-6= moderate pain, 7-10= severe untearable pain.
次要结局
- Number of patients with pain recurrence(1 week, 1, and 3 months)
- analgesic consumption(1 week, 1, and 3 months)
- Incidence of treatment related adverse events(immediately after injection)
研究者
Mina Maher
Ass professor anesthesia and pain
Minia University
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