Ultrasound Guided Serratus Anterior Versus Erector Spinae Block in Pain Alleviation in Acute Herpes Zoster
Not Applicable
Not yet recruiting
- Conditions
- Acute Herpes Zoster Neuropathy
- Registration Number
- NCT06476080
- Lead Sponsor
- Minia University
- Brief Summary
Acute herpes zoster pain is very severe . Conventional analgesics may be of no value. Regional blocks may play a role
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
- Adult population between 30 and 75 years old.
- Unilateral painful thoracic herpetic eruption of less than one week duration.
- VAS more than or equal 4, persistent pain in spite of proper antiviral and analgesic therapy, (800 mg oral acyclovir, 5 times per day, for one week), pregabalin 300 mg per day, acetaminophen 1000 mg per day, topical calamine lotion).
Exclusion Criteria
- Diabetic patients.
- Painful herpetic eruptive vesicles more than one week.
- Abdominal herpetic eruptions.
- Non-compliant on anti-viral (bulbar palsy for example).
- Co-malignancy or radiotherapy.
- Steroid therapy > 5 mg prednisolone or its equivalent.
- Infections or hematoma at site of injection.
- Coagulopathy (chronic kidney or liver disease, clopidogrel use).
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method pain score immediate after injection, 1 week, 1, 3 months Visual analogue scale from 0 to 10. 0= NO pain, 1-3=mild tolerable pain, 4-6= moderate pain, 7-10= severe untearable pain.
- Secondary Outcome Measures
Name Time Method Number of patients with pain recurrence 1 week, 1, and 3 months Number of patients in need for re-injection
Incidence of treatment related adverse events immediately after injection hypotension, bradyarrhythmia, hematoma
analgesic consumption 1 week, 1, and 3 months total amount dose of analgesics used