JPRN-jRCTs051190061已完成2 期
Efficacy of Pediococcus acidilactoci K15 strain on allergic symptoms related to Japanese cedar pollinosis during the pollen dispersal season: A randomized double-blind, placebo-controlled trial
Yamamoto Masashi0 个研究点目标入组 40 人开始时间: 2019年10月16日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
A tendency to suppress Japanese cedar pollenosis symptoms caused by natural exposure was observed after 12 weeks of intake of K15 lactobacillus, but the difference was not statistically significant. There are no safety issues and continuity is good.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 <= 64age old（—）
- 性别
- All
入选标准
- •1.individuals aged from 12 to 64 who will give informed consent upon their will
- •2.individuals who had allergic symptoms such as sneezing, rhinorrhea, nasal obstruction and eye itching during Japanese cedar pollen dispersal season in the past two consecutive years
- •3.individuals who had shown positive IgE titer more than class II for Japanese cedar pollen in the past three years
- •4.individuals who can take test material every day and who live or work in Osaka Prefecture
排除标准
- •1.Individuals who show more than class 5 titer of IgE for house dust mite or who show more than class 5 titer of IgE for pets (dogs or cats) and keep corresponding pets at home
- •2.Individuals who show more titer of IgE for house dust mite that that for Japanese cedar pollen
- •3.individuals receiving allergen (Japanese cedar pollen) immunotherapy or those who will receive allergen immunotherapy during the study
- •4.individuals with active diseases,thus,are judged to be inappropriate to join the study by their primary care physicians
- •5.individuals who are pregnant and brest-feeding and will have a plan of pregnancy during the study
- •6.individuals who habitually intake prebiotics or probiotics (more than 3 days in a week)
- •7.individuals who join other clinical studies
研究者
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