ACTRN12613000754741终止3 期
The ASPREE-Knee Sub-study: Does aspirin slow the progression of knee structural damage in adults over 70 years of age?
适应症
试验速览
- 阶段
- 3 期
- 状态
- 终止
- 入组人数
- 165
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 70 Years 至 o limit（—）
- 性别
- All
入选标准
- •Randomised ASPREE participants in Melbourne (Age >=70 years, free of previous cardiovascular disease or stroke, have preserved intellectual function and have no known life-limiting illness)
- •Aged 70 and over
- •Able and willing to provide informed consent
排除标准
- •1)As for ASPREE (Cardiovascular disease, impaired intellectual function, life limiting illness);
- •2)People with planned or prior knee joint replacement surgery of the dominant knee; unable to walk independently (no stick or frame).
- •3)People with rheumatoid arthritis, other inflammatory arthritis, or significant knee injury;
- •4)People undergoing arthroscopy or open surgery in the index knee in the last 12 months;
- •5)People receiving intra-articular therapy in the index knee in the last 12 months;
- •6)Any contraindication to MRI scanning (e.g. implanted pacemaker, metal sutures, presence of shrapnel or iron filings in the eye, or claustrophobia).
研究者
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