Endometrial immune profiling: a new perspective for pregnancy morbidity risk assessment in systemic lupus erythematosus - a pilot study
- Conditions
- lupusSLE10003816
- Registration Number
- NL-OMON56787
- Lead Sponsor
- Reumatologie en Klinische Immunologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
SLE patients
- Fulfilling ACR or SLICC or EULAR/ACR criteria for SLE
- No use of hormonal or intrauterine device anti-contraceptive
- Premenopausal
- Written informed consent
- > 18 years old and *wilsbekwaam*
Healthy women
- No systemic autoimmune disease
- No use of hormonal or intrauterine device anti-contraceptive
- Premenopausal
- Written informed consent
- > 18 years old and *wilsbekwaam*
Exclusion Criteria
- Other autoimmune diseases
- History of abnormal uterine cavity, major gynaecological surgery such as
hysterectomy or salpingectomy,, endometriosis or previous reproductive-assisted
invasive therapy
- Malignancies
- In case of healthy controls: repeated pregnancy loss or known difficulties to
become pregnant (infertility)
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method