JPRN-UMIN000008060CompletedPhase 4
Randomized trial of Lipid lowering Therapy for Endothelial Function;Statin Monotherapy Compared with Statin/Ezetimibe or Statin/Eicosapentaenoic Acid Combination Therapy - Rapid Estimate
Fukuoka wajiro hospital0 sites80 target enrollmentStarted: May 31, 2012Last updated:
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Enrollment
- 80
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 20years-old to 100years-old (—)
- Sex
- All
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1.Patients with liver disease (ALT or AST level is over 100IU/L, total Bil level is over 2.5mg/dl). 2.Patients with renal insufficiency (serum creatinine level is over 2.0mg/dl, or creatinine clearance is under 30mL/min/1.73m2). 3.Patients with congenital heart disease. 4.Patients within 3 months from myocardial infarction and with highly advanced cardiac dysfunction. 5.Patients with endocrine disease. 6.Patients with malignancy or inflammatory disease. 7.Patinets with highly advanced respiratory disease (containing pulmonary arterial pulmonary hypertension. 8.Patients with cranial nerve disease or locomotor apparatus disease, and severely compromised daily life. 9.Patients with severe hypertension. 10.Patients administrated steroid or immune suppressor. 11.Patients with type1 DM or poorly controled type2 DM(FBS>200mg/dl, HbA1c>10.0%) 12.Patients during pregnancy or with possibility of pregnancy. 13.Patients administrated catecholamine. 14.Patients with symptomatic hypotension. 15.Patients with significant LVOT obstruction (Hypertrophic obstructive cardiomyopathy or aortic stenosis). 16.Patients recognized inadequate by primary doctor.
Investigators
Similar Trials
Completed
Not Applicable
Randomized controlled trial of the lipid-lowering therapy with rosuvastatin and atorvastatin for the patients with coronary artery disease treated with percutaneous coronary interventiocoronary artery diseaseJPRN-UMIN000014342Hirosaki University Graduate School of Medicine300
Completed
Not Applicable
Substudy of lipid lowering trial on prevention of atherosclerosis in 75 or older on cholesterol absorption and synthesisHyper-LDL-cholesterolemiaJPRN-UMIN000002292International University of Health and Welfare1,000
Recruiting
Not Applicable
Examination of the optimal lipid-lowering therapy in patients with type 2 diabetes complicated with dyslipidemiatype 2 diabetes complicated with dyslipidemiaJPRN-UMIN000006537Department of Endocrinology and Metabolism Kyoto Prefectural University of Medicine, Graduate School of Medical Science30
Completed
Not Applicable
Effects of Aggressive Lipid Lowering Therapy With Atorvastatin on the Fibrous cap Thickness of Thin-cap Fibroatheroma: Three-Vessel Optical Coherence Tomography and Intravascular Ultrasound StudyAcute Coronary SyndromeJPRN-UMIN000003620Hyogo College of Medicine Cardiovascular Division50
Completed
Not Applicable
Ezetimibe lipid lowering trial on cholesterol absorption-synthesis and prevention of atherrosclerosis in 75 or older with hight risk hyper LDL cholesterolemiaHyper-LDL-cholesterolemiaJPRN-UMIN000017769International University of Health and Welfare1,300