Effect of varying(changing) the time interval between Fentanyl(opioid analgesic/pain relieving agent) and Etomidate (sedative/sleep inducing agent used for anaesthesia) administration on Etomidate requirement for induction(starting) of anaesthesia.
Not Applicable
- Registration Number
- CTRI/2021/08/035515
- Lead Sponsor
- jubilee mission medical college
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)Patients who will give consent to take part in this study
2)Age group 18 to 60 years
3) American Society of Anesthesiologists (ASA) physicalstatus classI, II
, III
4)Patients scheduled for elective surgery under GA
Exclusion Criteria
1)Patient refusal for studyparticipation
2)ASA class IV and V
3)Allergic to etomidate and fentanyl
4)Presence of preexisting neurological orneuromuscular disorders
5)BMI >35 in females and >40 males (morbidly obese patients)
6)Patients with severe cardiovascular disease (NYHA 3, NYHA 4)
7)Psychiatric patients and patients onpsychotropic drugs
8) Parturient and breast-feeding mothers
9) Patients having adrenal pathology and septic patients (higher risk of
adrenalsuppression
Study & Design
- Study Type
- BA/BE
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method : To determine whether fentanyl would significantly reduce the <br/ ><br>dosage of etomidate required to abolish response to verbal commands or loss of <br/ ><br>response to noxious stimulusTimepoint: The response will be noted at the time end point of inductionwhich will take less than 10 minutes
- Secondary Outcome Measures
Name Time Method To determine the relation between dosage of etomidate and <br/ ><br>end point of sedation during etomidate anesthesia with fentanyl at varying time <br/ ><br>intervals. <br/ ><br>Timepoint: 18 months