The efficacy and safety of curcumin for pain relief in chronic kidney disease patients with knee osteoarthritis

Phase 3

• Conditions: - osteoarthritis - chornic kidney disease; Curcuminoids, efficacy, osteoarthritis, Chronic Kidney Disease, Side effect

• Registration Number: TCTR20191106006
• Lead Sponsor: Faculty of medicine, prince of songkla university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-10-27
• Study Start: 2019-11-06
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

1. Over 18 years old
2. CKD phase 3 - 4
3. Was diagnosed with osteoarthritis At the knee joint according to the Altman criteria and can match Kellgren-Lawrence grade 2 - 3 and have pain.

Exclusion Criteria

1. pregnant
2. Underlying cirrhosis, hepatitis, bile duct disease or disease, cancer
3. Acute kidney injury, myocardial infartion
4. Curcumin allergy
5. Have a history of curcumin Or supplements that contain curcumin. Herbs or dietary supplements that reduce pain during the 2 months before the study.
6. Have a history of chondroitin sulfate, glucosamine, intraarticular hyaluron during the 2 months before the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
pain 12, 24 weeks WOMAC pain subscale ,Quality of life 12, 24 weeks EQ5D5L,anxiety 12, 24 weeks Hospital anxiety and depression

Secondary Outcome Measures

Name	Time	Method
side effect 12, 24 weeks physical examination