Comparing how two different doses of an additive to bupivacaine heavy modifies the duration of action when used in lower limb surgeries
Phase 3
- Conditions
- Health Condition 1: S899- Unspecified injury of lower leg
- Registration Number
- CTRI/2022/01/039545
- Lead Sponsor
- Dr Ashik Sreekumar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All patients from age 18 to 65 belonging to ASA grade 1, 2 or 3 undergoing lower limb surgeries
Exclusion Criteria
Contraindications of spinal Anesthesia such as Local infection, raised intra cranial tension, coagulopathy , valvular heart disease
Known allergy to the study drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) Time of onset of sensory block. <br/ ><br>2) Maximum height of sensory block. <br/ ><br>3) Duration of sensory block as regression to L1. <br/ ><br>4) Time of onset of motor block. <br/ ><br>5) Duration of motor block. <br/ ><br>6) Duration of post operative analgesia. <br/ ><br>Timepoint: Sensory block will be tested every 2 min till maximum height of sensory level, Thereafter every 20 min till the block regression to L1 level. <br/ ><br> Motor block will be tested every 2 mins using Bromage scale till starting of surgery,Thereafter every 20 mins in the post op period till complete recovery (grade 0) and duration of motor block will be noted.
- Secondary Outcome Measures
Name Time Method Intra operative hemodynamic parameters eg Heart rate & Mean Blood Pressure <br/ ><br>Side effects such as nausea vomiting, pruritus, urinary retention and respiratory depression <br/ ><br>Timepoint: Every 2 min for the first 20 min and then every 10 min till the block regression to L1, post operative analgesia every 30 min for the first 2 hours and 2 hourly thereafter.