Evidence based prevention of cerebral palsy in preterm infants
Phase 3
- Conditions
- Cerebral palsy in preterm infants
- Registration Number
- JPRN-UMIN000008213
- Lead Sponsor
- EPOC study group
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 462
Inclusion Criteria
Not provided
Exclusion Criteria
1) Congenital anomaly (the accurate neurological abnormality and severe heart malformation) 2) Chromosomal aberration 3) Hydrops foetalis 4) IUGR (less than -3.0SD) 5) Severe asphyxia 6) The case found PVL at birth 7) The case that is understood inappropriate by doctors
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of CP or death at 1 year old to 1 year and half in corrected age
- Secondary Outcome Measures
Name Time Method 1) Incidence of PVL at 28 days and 1 year old to 1 year and half in corrected age 2) Severity of CP at 1 year old to 1 year and half in corrected age 3) Complete blood counts, liver function, renal function, blood sugar and blood pressure at 7 and 28 days 4) Incidence of Late-onset circulatory disorder within 28 days 5) Incidence of symptomatic patent ductus arteriosus within 28 days 6) Incidence of intracranial hemorrhage (Level 3-4) within 28 days 7) Administration of EPO for the improvement of anemia of prematurity within 28 days 8) Mortality at 1 year old to 1 year and half in corrected age