Is There a Comorbidity Between Migraine and Allergic Rhinitis?

Completed

• Conditions: Migraine; Allergic Rhinitis

• Registration Number: NCT01845051
• Lead Sponsor: Baskent University

Brief Summary

The researchers investigated the relationship between migraine and allergy. For this purpose, the researchers designed a controlled study to evaluate nasal symptoms and signs; and to perform Specific Immunoglobulin E (IgE) measurements in migraine patients and healthy subjects. According to these results the prevalence of allergic rhinitis in migraine group was planned to be compared to that of the healthy controls, statistically.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-11
• Primary Completion: 2013-03
• Study Completion: 2013-03
• Study First Submitted: 2013-04-29
• Status Verified: 2013-05
• Study First Submitted QC: 2013-05-01
• Last Update Submitted: 2013-05-01
• Study First Posted: 2013-05-03
• Last Update Posted: 2013-05-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• patients with migraine

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Exclusion Criteria

• other neurologic disorders that may contribute to headaches, such as stroke, cerebral palsy, trigeminal neuralgia, and seizure disorder
• also acute and chronic sinusitis.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Specific Immunoglobulin E (IgE)	1 day	Blood samples were taken from study and control group for the determination of Specific IgE panel against six different allergens: (1) fungi, (2) grass pollens, (3) tree pollens, (4) wild herbs, (5) mite 1, (6) mite 2. For all of specific IgE panels, \<0,7 RU/ml was negative; and \>0,7 RU/ml was Positive.
Nasal Symptom Scores	1 day	Symptoms were assessed with a questionnaire for the presence and severity of allergic rhinitis (AR) symptoms on a scale of 0-3 (0 = none, 1 = mild, 2 = moderate, 3 = severe). Symptoms of AR (Nasal discharge, nasal congestion, itching and sneezing) were graded between 0-3.