The effect of ondansetron on persisting vomitin in children with gastro-enteritis presenting at primary care out of hours service.
- Conditions
- Huisartsgeneeskunde (General Practice), Kinderen (Children), Gastro-enteritis (gastroenteritis), Kosteneffectiviteit (cost-effectiveness), Misselijkheid (vomiting)
- Registration Number
- NL-OMON26937
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 220
Inclusion Criteria
1.Aged 6 months to 6 years;
2.At least four reported episodes of vomiting or diarrhoea during the last twenty-four hours preceding presentation
Exclusion Criteria
1.Use of anti-emetics in the previous 6 hours;
2.Known renal failure or hypoalbuminemia (as this could affect the assessment of hydration status);
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The proportion of children that continue to vomit within the first 4 hours after presentation at the OHS with acute gastro-enteritis.<br><br>
- Secondary Outcome Measures
Name Time Method Cessation of vomiting, the number of vomiting episodes during ORT, referral to a (pediatric) emergency department), intravenous rehydration, hospital admission rate and duration, healthcare use and costs. A vomiting episode will be recorded by the parent when a forceful expulsion of stomach contents occurs. Episodes separated by no more than two minutes will be counted as a single episode. Nonproductive retching, spilling of oral contents, and drooling are not considered vomiting. Cessation of vomiting will be noted at the time of a vomiting episode after which no more than 1 vomiting episode is noted during a period of at least 1 day.