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临床试验/NCT04780139
NCT04780139已完成不适用

Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area for Prediction of Post Spinal Hypotension in Patients Undergoing Orthopedic Surgeries

Ain Shams University1 个研究点 分布在 1 个国家目标入组 62 人开始时间: 2021年3月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
62
试验地点
1
主要终点
Predictive value of internal jugular vein (IJV) cross sectional area.

研究概览

简要总结

The aim of this study is to evaluate the efficacy of internal jugular cross sectional area for predicting the occurrence of PSAH.

详细描述

The aim of this study is to evaluate the efficacy of internal jugular cross sectional area for predicting the occurrence of PSAH. Spinal anaesthesia is frequently used in daily clinical practice. Postspinal anaesthesia hypotension (PSAH) is a common side effect with an incidence of 15.3 to 33% that may result in organ hypoperfusion and ischaemic events. Patients' susceptibility to intraoperative hypotension can be influenced by the sensory block level, age, preoperative volume status , physical status, pre-operative medications and fasting.

PSAH due to spinal blockade is principally a consequence of diminished systemic vascular resistance after blockade of preganglionic sympathetic fibres. Many attempts have been tried to prevent PSAH, such as intravenous volume preload or prophylactic vasopressors. However, fluid infusion has been proved to lower the incidence of PSAH and significantly decrease vasopressor requirements. At the same time, empirical volume loading carries the potential of volume overload, particularly in patients with cardiac disease. Consequently, the search for predictors of PSAH is becoming mandatory to avoid blind volume loading and reserve it only for patients who are expected to develop PSAH. .

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研究设计

研究类型
Observational
观察模型
Ecologic Or Community
时间视角
Prospective

入排标准

年龄范围
40 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients more than 40 years of age.
  • American Society of Anesthesiologists' (ASA) physical status 1 or
  • scheduled for elective surgery under spinal anaesthesia in the supine position.

排除标准

  • BMI more than 35 kg m
  • taking angiotensin converting enzyme inhibitors.
  • pregnant women.
  • emergency cases.
  • absolute or relative contraindications to spinal anaesthesia.
  • Also, patients with a baseline arterial systolic blood pressure less than 90 mmHg or mean arterial blood pressure (MBP) less than 70 mmHg will be excluded.

结局指标

主要结局

Predictive value of internal jugular vein (IJV) cross sectional area.

时间窗: 30 minutes

The primary outcome is to evaluate the predictive value of internal jugular diameter cross sectional area for detecting PSAH

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Walid Nofal

Assisstant professor

Ain Shams University

研究点 (1)

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