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Clinical Trials/NCT04780139
NCT04780139
Completed
Not Applicable

Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area for Prediction of Post Spinal Hypotension in Patients Undergoing Orthopedic Surgeries

Ain Shams University1 site in 1 country62 target enrollmentMarch 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Post-spinal Anesthesia Hypotension
Sponsor
Ain Shams University
Enrollment
62
Locations
1
Primary Endpoint
Predictive value of internal jugular vein (IJV) cross sectional area.
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The aim of this study is to evaluate the efficacy of internal jugular cross sectional area for predicting the occurrence of PSAH.

Detailed Description

The aim of this study is to evaluate the efficacy of internal jugular cross sectional area for predicting the occurrence of PSAH. Spinal anaesthesia is frequently used in daily clinical practice. Postspinal anaesthesia hypotension (PSAH) is a common side effect with an incidence of 15.3 to 33% that may result in organ hypoperfusion and ischaemic events. Patients' susceptibility to intraoperative hypotension can be influenced by the sensory block level, age, preoperative volume status , physical status, pre-operative medications and fasting. PSAH due to spinal blockade is principally a consequence of diminished systemic vascular resistance after blockade of preganglionic sympathetic fibres. Many attempts have been tried to prevent PSAH, such as intravenous volume preload or prophylactic vasopressors. However, fluid infusion has been proved to lower the incidence of PSAH and significantly decrease vasopressor requirements. At the same time, empirical volume loading carries the potential of volume overload, particularly in patients with cardiac disease. Consequently, the search for predictors of PSAH is becoming mandatory to avoid blind volume loading and reserve it only for patients who are expected to develop PSAH. . .

Registry
clinicaltrials.gov
Start Date
March 1, 2021
End Date
July 21, 2021
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Walid Nofal

Assisstant professor

Ain Shams University

Eligibility Criteria

Inclusion Criteria

  • patients more than 40 years of age.
  • American Society of Anesthesiologists' (ASA) physical status 1 or
  • scheduled for elective surgery under spinal anaesthesia in the supine position.

Exclusion Criteria

  • BMI more than 35 kg m
  • taking angiotensin converting enzyme inhibitors.
  • pregnant women.
  • emergency cases.
  • absolute or relative contraindications to spinal anaesthesia.
  • Also, patients with a baseline arterial systolic blood pressure less than 90 mmHg or mean arterial blood pressure (MBP) less than 70 mmHg will be excluded.

Outcomes

Primary Outcomes

Predictive value of internal jugular vein (IJV) cross sectional area.

Time Frame: 30 minutes

The primary outcome is to evaluate the predictive value of internal jugular diameter cross sectional area for detecting PSAH

Study Sites (1)

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