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临床试验/NCT05352789
NCT05352789已完成不适用

Exploration of Nutrition and Metabolic Prehabilitation Practices for Haematopoietic Stem Cell Transplant (HSCT) in UK and ROI Transplant Centres: A BSBMT Multi-centre Survey

Nottingham University Hospitals NHS Trust1 个研究点 分布在 1 个国家目标入组 66 人开始时间: 2020年8月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
66
试验地点
1
主要终点
To understand the routine screening, assessment and management practices of nutritional and metabolic parameters prior to haematopoeitic stem cell transplantation in UK centres

研究概览

简要总结

To explore current practices of nutrition and metabolic screening, assessment and management prior to Haematopoietic Stem Cell Transplant (HSCT) in UK and ROI transplant centres.

Nutrition and metabolic parameters assessed in the survey include glycaemic control, lipid function, liver function, nutritional screening, nutritional assessment, nutrition intervention (tube feeding, diet, micronutrient) and exercise.

This work will be used to inform the design of a UK dual centre feasibility study of personalised nutrition and metabolic care for HSCT patients prior to transplantation.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Other

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • BSBMT registered adult HSCT centres (including TYA services where patients have opted to be treated in an adult service pathways)
  • Centres delivering either autologous or allogeneic stem cell transplants

排除标准

  • All paediatric HSCT services

结局指标

主要结局

To understand the routine screening, assessment and management practices of nutritional and metabolic parameters prior to haematopoeitic stem cell transplantation in UK centres

时间窗: Aug 20- March22

full survey completion: see parameters below

Differences in enteral feeding practices prior to HSCT across UK and ROI HSCT centres and between health professionals

时间窗: Aug 20-March22

g. Enteral feeding: Routine inclusion of enteral feeding prior to HSCT will be assessed using 2 mandatory questions, 1 - categorical. Practical details of types of enteral feeding tubes 2 questions (1 - categorical questions, 1 free text)

Differences in frequency of assessments of liver and renal function prior to HSCT across UK and ROI HSCT centres and between health professionals

时间窗: Aug 20-March22

c. Liver and renal function screening frequency will be asked: 1. How often would you measure liver/kidney function as blood samples prior to HSCT? (likert scale - Always, often, sometimes, rarely, never); 2. How often would you measure liver/kidney function using a scan prior to HSCT? (likert scale - Always, often, sometimes, rarely, never)

Differences in physical assessment, advice and delivery prior to HSCT across UK and ROI HSCT centres and between health professionals

时间窗: Aug 20-March22

i. Exercise: As part of routine practice how often do patients receive exercise advice prior to HSCT? (likert response: Always, often, sometimes, rarely, never); As part of "routine practice" how often do your patients have their activity levels measured prior to HSCT i.e. questionnaire or physical assessment? response: Always, often, sometimes, rarely, never); and 2 multi select questions to determine professionals delivering care.

Differences in frequency of glycaemic screening prior to HSCT across UK and ROI HSCT centres and between health professionals

时间窗: Aug 20-March22

a) Glycaemic screening will be assessed by 2 responses: How often would you measure blood glucose and urinary glucose prior to HSCT? (likert scale - Always, often, sometimes, rarely, never)

Differences in nutritional screening and assessment practices done prior to HSCT across UK and ROI HSCT centres and between health professionals

时间窗: Aug 20-March22

d. Nutritional screening and assessment: Routine inclusion of nutritional screening and assessment practices prior to HSCT will be assessed using 4 mandatory questions, 3 - yes/no/unsure and 1 categorical question. Practical details of strategies of assessment and measurement will be assessed using 5 categorical questions and 6 free text questions.

Differences in body composition assessments given prior to HSCT across UK and ROI HSCT centres and between health professionals

时间窗: Aug 20-March22

e. Assessment of body composition: Routine inclusion of body composition assessment prior to HSCT will be assessed using 2 mandatory questions, 1 - yes/no/unsure and 1 categorical question. Practical details of strategies of assessment and measurement will be assessed using 2 categorical questions and 3 free text questions.

Differences in dietary advice given prior to HSCT across UK and ROI HSCT centres and between health professionals

时间窗: Aug 20-March22

f. Dietary advice: Routine inclusion of dietary advice prior to HSCT will be assessed using 3 mandatory questions, 1 - yes/no/unsure and 2 - five point likert scales (definitely = 4, very probably = 3, probably=2, probably not = 1, definitely not =0). Practical details of types of dietary advice and strategies for implementation will be assessed using 2 categorical questions, 2 free text questions and 3 - six point likert scaled consensus statements (Always= 5, very frequently = 4, occasionally = 3, rarely = 2, very rarely = 1, never = 0)

Differences in specialist dietary advice given prior to HSCT across UK and ROI HSCT centres and between health professionals

时间窗: Aug 20-March22

h. Micronutrient supplementation: Routine inclusion of micronutrient advice prior to HSCT will be assessed using 1 mandatory question, yes/no/unsure format. Practical details of micronutrient supplementation practices using 1 categorical questions and 1 free text question.

Differences in frequency of assessments of lipid profile screening prior to HSCT across UK and ROI HSCT centres and between health professionals

时间窗: Aug 20-March22

b. Lipid parameters: How often would you measure blood glucose and urinary glucose prior to HSCT? (likert scale - Always, often, sometimes, rarely, never)

次要结局

  • To understand perceptions on the role and value of prehabilitation in HSCT(Aug 20-March22)
  • Perceptions on best composition of prehabilitation programme prior to HSCT.(Aug 20-March22)
  • Description of current HSCT prehabilitation services in adult services in UK and ROI(Aug 20-March22)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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