NCT04270006Unknown早期 1 期
Effect of Adipose Derived Stem Cells Exosomes as an Adjunctive Therapy to Scaling and Root Planning in the Treatment of Periodontitis: A Human Clinical Trial
适应症
试验速览
- 阶段
- 早期 1 期
- 入组人数
- 10
- 试验地点
- 4
- 主要终点
- change in Bone level
研究概览
简要总结
The adipose stem cells exosomes will be extracted from adipose stem cells isolated autogenously from the patient to be injected locally into the periodontal pockets in order to evaluate their regenerative effect.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Advanced periodontitis (Stage III or IV)
- •Healthy patients.
排除标准
- •Smokers, Diabetic, Pregnant ladies, Under corticosteroids or contraceptive treatment,poor oral hygiene.
结局指标
主要结局
change in Bone level
时间窗: 0 and 6 months
Cone beam C.T (CBCT)
change in pocket depth
时间窗: 0, 3 and 6 months
Probing depth (PD)
change in attachment level
时间窗: 0, 3 and 6 months
Clinical attachment level (CAL)
change in gingival inflammation
时间窗: 0, 3 and 6 months
Gingival index (GI)
次要结局
未报告次要终点
研究者
Ebtehal Mohammed
Lecturer of oral medicine, periodontotlogy and oral diagnosis
Beni-Suef University
研究点 (4)
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