Influence of Bananas Varying in Carbohydrate and Phenolic Content on Exercise Performance and Recovery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 23
- 试验地点
- 2
- 主要终点
- Change in total plasma concentrations of inflammatory cytokines
研究概览
简要总结
In a previous study at the Appalachian State University (ASU) Human Performance Laboratory at the North Carolina Research Campus (NCRC), investigators showed that cyclists ingesting about one-half of a banana with water every 15 minutes cycled 75-km faster (5%) than with water alone. The polyphenols (i.e., chemicals in plants with health benefits) in the banana improved the capacity to counter oxidative stress, and the sugars lowered post-exercise inflammation. The cyclists reported some gastrointestinal discomfort, however, from the high volume of bananas consumed. Dole Foods, the sponsor of this study, has a banana collection that includes many different varieties, including the Mini banana that has a higher sugar (50%) and phenolic (63%) content than the typical banana (Cavendish) available in stores. Thus athletes should experience similar performance benefits from a smaller volume of Mini compared to Cavendish bananas, and reduced gastrointestinal symptoms. If study results are favorable, Dole Foods may market the Mini banana as the "sport" banana.
The purpose of this study is to compare ingestion of Mini and Cavendish bananas with an equicaloric, sugar-only beverage or water on 75-km cycling performance and post-exercise oxidative capacity and stress, inflammation, immune function, muscle damage and soreness, and gastrointestinal symptoms.
详细描述
The research procedures will be conducted at the Human Performance Laboratory (Room 1201, Plants for Human Health Institute Building, 600 Laureate Way), operated by Appalachian State University at the North Carolina Research Campus (NCRC) in Kannapolis, NC. Participants will come here for orientation/baseline testing and then 4 exercise test sessions (with each including two additional lab visits to provide 1- and 2-day 7:00 am recovery blood samples) (thus 13 total lab visits). The total amount of time participants will be asked to volunteer for this study is about 35 hours at the Human Performance Laboratory (over a 7 to 8-week period).
ORIENTATION AND BASELINE TESTING:
One to two weeks prior to the first 75-km cycling time trial, participants will report to the NCRC Human Performance Lab for orientation/baseline testing. Participants will be screened to verify "low risk" status for cardiovascular disease, and provide voluntary consent. Demographic and training histories will be acquired with questionnaires.
Participants will be tested for VO2max (i.e., maximal oxygen consumption) using the Lodi cycle ergometer. The purpose of the VO2max test is to determine maximum exercise capacity. The time commitment is about 30 to 60 minutes, and participants will wear exercise clothes and shoes that allow for free movement during vigorous exercise. Participants will be rested, well nourished, and hydrated for the test and avoid alcohol, caffeine, and tobacco 3 hours before the test. Participants will avoid significant exertion or exercise the day of testing and report any medication that are being used to the testing staff before the test. The test will begin with an exercise warm-up period of a few minutes, and then participants will pedal at progressively harder workloads. The test will continue until participants become fatigued and decide to stop, or other symptoms prohibit further exercise. Both leg tiredness and breathlessness are common sensations of the fatigue that participants may experience. During the test, participants will wear a facemask that allows exhaled air to be analyzed, and a chest strap for heart rate monitoring. Participants will communicate with the lab personnel during the test by the use of a perceived exertion chart to indicate how the exercise feels.
Percent body fat will be measured using the BodPod. Participants will sit inside the BodPod with a tight-fitting swim suit for about 10 minutes while body fat is calculated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Healthy, with no known cardiovascular disease, diabetes, or cancer.
- •Non-smoker.
- •Regularly compete in road races (category 1 to 5) and/or capable of cycling 75 km in a laboratory setting (using own bicycles on CompuTrainer training systems).
- •Agree to train normally, maintain weight, and avoid the regular use of large-dose vitamin and mineral supplements, herbs, and medications that influence inflammation and immune function (in particular, Advil, Motrin, aspirin and similar anti-inflammatory drugs) for the duration of the 7 to 8-week study. If in doubt, discuss supplement/medication use with the Research Manager.
- •Categorized as "low risk" using the American College of Sports Medicine screening questionnaire.
排除标准
- •Inability to comply with study requirements.
- •Any other concurrent condition which, in the opinion of the primary investigator (PI), would preclude participation in this study or interfere with compliance.
- •Current diagnosis of cardiovascular disease, diabetes, or cancer (except for non-melanoma skin cancer).
结局指标
主要结局
Change in total plasma concentrations of inflammatory cytokines
时间窗: Pre-exercise, and post-exercise (0, 0.75, 1.5, 3.0, 4.5, 21, 45 hours)
Total plasma concentrations of five inflammatory cytokines \[monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor alpha (TNFα), IL-6, IL-8, and IL-10\] will be determined using an electrochemiluminescence based solid-phase sandwich immunoassay (Meso Scale Discovery, Gaithersburg,MD, USA).
次要结局
- Change in concentration of serum myoglobin(Pre-exercise, and post-exercise (0, 0.75, 1.5, 3.0, 4.5, 21, 45 hours))
- Change in muscle concentration of glycogen(Pre-exercise, and post-exercise (0 hours))
- Change in self-reported gastrointestinal and mental symptoms from a short questionnaire(Pre-exercise, and post-exercise (0 hours))
- Change in concentration of ferric reducing ability of plasma (FRAP)(Pre-exercise, and post-exercise (0, 0.75, 1.5, 3.0, 4.5, 21, 45 hours))
- Change in plasma concentration of oxidized low density lipoprotein(Pre-exercise, and post-exercise (0, 0.75, 1.5, 3.0, 4.5, 21, 45 hours))
- Change in blood natural killer cell activity(Pre-exercise, and post-exercise (0, 0.75, 1.5, 3.0, 4.5, 21, 45 hours))