NCT00446758已完成3 期
Trial of Zinc and HIV Progression in Children
Harvard School of Public Health (HSPH)1 个研究点 分布在 1 个国家目标入组 440 人开始时间: 2008年3月1日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 440
- 试验地点
- 1
- 主要终点
- Morbidity from respiratory and diarrheal infections, HIV disease progression
研究概览
简要总结
To examine whether daily oral zinc supplementation to HIV-infected Tanzanian preschool children reduces diarrheal and respiratory morbidity, delays HIV disease progression, and improves growth.
详细描述
The purpose of this study is to examine whether daily oral zinc supplementation to HIV-infected Tanzanian preschool children reduces diarrheal and respiratory morbidity, delays HIV disease progression, and improves growth.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 6 Weeks 至 60 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •HIV Infected Children under 60 months of age presenting at HIV treatment clinics in Dar es Salaam, Tanzania
排除标准
- •Eligible for ART: CD4 cell counts < 20% or above pediatric clinical stage of HIV disease 3 according to WHO staging system.
- •Severe acute malnutrition; Major congenital malformations
结局指标
主要结局
Morbidity from respiratory and diarrheal infections, HIV disease progression
时间窗: every 4 to 6 months until the end of follow-up
次要结局
- growth in height and weight(every 4 to 6 months until the end of follow-up)
研究者
Eduardo Villamor
Adjunct Associate Professor of International Nutrition
Harvard School of Public Health (HSPH)
研究点 (1)
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