CTRI/2021/05/033356
Not yet recruiting
Phase 4
A comparison of efficacy and safety of topiramate and amitriptyline Vs amitriptyline alone in chronic migraine : A randomized controlled trial.
Principal Investigator Prof Jayantee Kalita0 sites0 target enrollmentTBD
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Health Condition 1: G437- Chronic migraine without auraHealth Condition 2: G438- Other migraine
- Sponsor
- Principal Investigator Prof Jayantee Kalita
- Status
- Not yet recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •patients with chronic migraine attending neurology service will be included
- •diagnosis of chronic migraine will be based on ICHD\-3 beta criteria (2013\)\-
- •adults \>18 to \<55 years of age
- •h/o at least 8 attacks of migraine (with or without aura )per month in last 3 months
- •h/o \>15 headache days per month for \>3 months
- •history of migraine (with or without aura)for \>12 months prior to enrollment
Exclusion Criteria
- •patients with uncontrolled diabeties/hypertension ,heart diseases,psychiatric disease,seizures,hearing deficit,ear disease,visual deficit,stroke like illness,infection,organ failure,malignancy,asthamatics,immunosuppressant,systemic disease,age \<18 or \>55 years ,migraine onset after 50 years of age ,on prophylactic treatment in past one month ,abortive medication with opioid drugs,pregnancy,and unwilling for consent
Outcomes
Primary Outcomes
Not specified
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