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Clinical Trials/NCT07371000
NCT07371000
Recruiting
Not Applicable

Early Detection of Overactive Bladder and Elimination of Negative Impact on Quality of Life

Institute of Health Information and Statistics of the Czech Republic20 sites in 1 country1,000 target enrollmentStarted: September 1, 2025Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Sponsor
Institute of Health Information and Statistics of the Czech Republic
Enrollment
1,000
Locations
20
Primary Endpoint
Pilot testing with 1,000 participants

Overview

Brief Summary

Overactive bladder (OAB) is one of the most common health problems in the adult population. The goal of this project is to improve the awareness of the problem and to correctly refer the targeted persons to a specialist or a doctor. This will be provided by an online screening tool, designed as web platform and mobile application, where the data will be stored in respect to GDPR. People with a positive result from the online screening tool will be offered an examination by a specialist (gynaecologist, urogynaecologist, urologist) involved in the project. The specialist will have access to the results from the online screening tool - he/she will log into the web platform with a view of the participants profile. He/she will perform the diagnosis, confirm or refute the diagnosis and complement it with any further diagnostic tests and set the standard treatment.

Detailed Description

Overactive bladder (OAB) is one of the most common health problems in the adult population (15-20% prevalence), with just under half of those affected seeking professional medical help. The goal of this project is to improve the awareness of the problem and to correctly refer the targeted participants to a specialist or a doctor who is knowledgeable about the problem and who will set up an adequate therapy.

A targeted PR campaign will direct those interested in joining the pilot screening project to a website with information about OAB and information about the pilot screening process. The web platform will also guide the user to create a secure user profile to participate in the project, where they will complete validated questionnaires related to OAB, necessary personal and family history data to optimize follow-up diagnosis during the in-person examination with a specialist, and a validated questionnaire measuring quality of life. After completing the online screening tool, the user will be offered a referral to a specialist in the vicinity. Participation in the online screening tool will be conditional on checking the online Consent to Participate box and Consent to Disclose Personal Data in accordance with GDPR.

People with a positive result from the online screening tool will be offered an examination by a specialist (gynaecologist, urogynaecologist, urologist) involved in the project. The specialist will have access to the results from the online screening tool - he/she will log into the web platform with a view of the participant's profile. He/she will perform the diagnosis, confirm or refute the diagnosis and complement it with any further diagnostic tests and set the standard treatment.

The data collected will be used to properly evaluate the pilot project in line with its objectives. An analysis of the problems and risks of the project with regard to the whole pilot screening process and a simplified cost evaluation will also be carried out.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Screening
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Signed Consent to Participate in the Project and Consent to the Processing of Personal Data (online and paper format)
  • Men and women over 18 years of age with increased urinary frequency (more than 7 times in 24 hours)
  • Optional inclusion criteria:
  • \- Nycturia and/or urge incontinence.

Exclusion Criteria

  • Unsigned Consent to Participate in the Project and Consent to the Processing of Personal Data.
  • Current treatment of OAB, acute problems, suspicion of another disease causing OAB symptoms (haematuria, suspected bladder cancer, etc.)
  • Inflammation of the lower urinary tract.

Arms & Interventions

OAB Screening Arm

Other

Participants matching all the inclusion & exclusion criteria will undergo a standardized screening process for the diagnosis of OAB. This process involves the use of an online screening self-testing tool, where the data from individual questionnaires specific to OAB diagnosis will be evaluated by a specialist.

Intervention: Standardized Screening Protocol (Other)

Outcomes

Primary Outcomes

Pilot testing with 1,000 participants

Time Frame: From enrollment to the end of examination in 3 months

Pilot testing of the procedure on a sample of 1,000 people who will undergo an online self-diagnostic screening tool and be examined by a urogynecologist/urologist.

Number of participants (completion of anonymous screening test)

Time Frame: from enrollment up to 1 week

Number of participants who complete anonymous screening test based on three questions reffering to urology health

Percentage of people with suspected OAB who agreed to participate in a follow-up examination with specialist

Time Frame: From enrollment up to 3 months

Percentage of people with a specialist confirmed diagnosis of OAB at the face-to-face visit

Time Frame: Through study completion, an average of 6 months

Percentage of people who attended follow-up examination after 3 months

Time Frame: Through study completion, an average of 9 months

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Institute of Health Information and Statistics of the Czech Republic
Sponsor Class
Other Gov
Responsible Party
Sponsor

Study Sites (20)

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