NCT04629326招募中不适用
PD-L1 Targeting Molecular Imaging of Solid Tumors
Peking University Cancer Hospital & Institute1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2021年7月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Standardized uptake value（SUV）
研究概览
简要总结
The objective of the study is to constrcut a noninvasive approach WL12 PET/CT to detect the PD-L1 expression of tumor lesions in patients with gastrointestinal tumors and to identify patients benefiting from anti-PD-1/L1 treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •1. Aged >18 years old; ECOG 0 or 1;
- •2. Patients with Gastrointestinal tumors;
- •3. Has at least one measurable target lesion according to Response Evaluation Criteria in Solid Tumors (RECIST V1.1);
- •4. life expectancy >=12 weeks.
排除标准
- •1. Significant hepatic or renal dysfunction;
- •2. Is pregnant or ready to pregnant;
- •3. Cannot keep their states for half an hour;
- •4. Refusal to join the clinical study;
- •5. Suffering from claustrophobia or other mental diseases;
- •6. Any other situation that researchers think it is not suitable to participate in the experiment.
结局指标
主要结局
Standardized uptake value（SUV）
时间窗: 2 years
The uptake of the tracer in the primary and metastatic tumor lesions by measuring standardized uptake value（SUV）on PET/CT
次要结局
未报告次要终点
研究者
Hua Zhu
Associate Professor
Peking University Cancer Hospital & Institute
研究点 (1)
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