iver protective effect of Tinospora Cordifolia plant (Guduchi) in TB patients
Phase 2
- Conditions
- Health Condition 1: A150- Tuberculosis of lung
- Registration Number
- CTRI/2024/07/071071
- Lead Sponsor
- Dayananda Sagar University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Age: 18-75 years
TB patients on standard ATT regimen (INH & Rifampicin)
Exclusion Criteria
Drug resistant TB
ALT, & AST more than 5x ULN at baseline
Bilirubin more than 2x ULN at baseline
Pregnancy and Lactation
Concomitant use of glibenclamide and immunosuppressants
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Patients exhibiting improvements in their clinical symptoms: levels of bilirubin, ALT, AST, and HMGB1, GGT and Glutathione and other clinical indicators of liver function will be within the normal rangeTimepoint: 2 months
- Secondary Outcome Measures
Name Time Method Altered levels of levels of bilirubin, ALT, AST, and HMGB1, GGT and Glutathione and other clinical indicators of liver functionTimepoint: 2 months