Comparison of Early Versus Late Trophic Feeding in Preterm Very Low Birth Weight Neonates at a Tertiary Care Hospital
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Incidence of necrotizing enterocolitis
研究概览
简要总结
Local data on the neonatal outcomes in early versus late trophic feeding in preterm very low birth weight neonates in terms of mean hospital stay is scarce. Therefore, the current study was planned with the objective of comparing the neonatal outcomes in early versus late trophic feeding in preterm very low birth weight neonates in terms of mean hospital stay.
详细描述
Since preterm, very low birth weight births are common in society, an effective treatment modality is needed at the moment. Evaluating the length of hospital stay and occurrence of necrotizing enterocolitis in preterm very low birth weight neonates with respect to two approaches of trophic feeding in local settings will provide an insight into a better implementation of preventive strategies, resulting in reducing the hospital stays and the incidence of necrotizing enterocolitis, and hence reducing the burden on the already meager resources.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 1 Day 至 30 Days（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Any gender
- •Neonates aged 1-30 days
- •Preterm very low birth weight neonates
排除标准
- •Neonates transferred from other hospital and already started on antibiotics.
- •Neonates with congenital anomalies, hypoxic ischemic encephalopathy, central nervous system (CNS) impairment, neonatal sepsis, urinary tract infection, or one of twins or higher order multiples (on history and medical record).
- •Non-consenting parents.
研究组 & 干预措施
Early trophic feeding group
Infants will receive trophic (enteral) feeding within the first 48 hours after birth.
干预措施: Early trophic feeding (Dietary Supplement)
Late trophic feeding group
Infants will receive trophic (enteral) feeding after 72 hours after birth.
干预措施: Late trophic feeding (Dietary Supplement)
结局指标
主要结局
Incidence of necrotizing enterocolitis
时间窗: Up to 30 days
Confirmation of the occurrence of necrotizing enterocolitis based on modified Bell's diagnostic criteria
次要结局
- Hospital stay(through study completion, an average of 1 month)
研究者
Muhammad Aamir Latif
Research Consultant
RESnTEC, Institute of Research