Transcutaneous Spinal Cord Stimulation for Freezing of Gait in Parkinson Disease
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Parkinson Disease
- Sponsor
- University of Sao Paulo General Hospital
- Enrollment
- 5
- Locations
- 1
- Primary Endpoint
- Freezing of gait score
- Last Updated
- 6 years ago
Overview
Brief Summary
Spinal cord stimulation has been used to treat gait problems in Parkinson's disease, with positive results along some studies. The use of non-invasive stimulation can be an alternative to stimulate the spinal corn.
Detailed Description
Spinal cord stimulation has been used to treat gait problems in Parkinson's disease, with positive results along some studies. The use of non-invasive stimulation can be an alternative to stimulate the spinal corn. In this pilot trial, the investigators recruit participants with Parkinson' disease and freezing of gait. The aim of the study is to explore the safety along the non-invasive magnetic thoracic spinal cord stimulation as well the effect on gait problems, especially freezing of gait, prospectively, in an open-label fashion.
Investigators
Rubens Gisbert Cury
Principal investigator
University of Sao Paulo General Hospital
Eligibility Criteria
Inclusion Criteria
- •diagnosis of advanced idiopathic Parkinson's disease
- •significant freezing of gait despite optimized treatment with medications and rehabilitation program
Exclusion Criteria
- •psychiatric symptoms
- •cardiac pacemaker
Outcomes
Primary Outcomes
Freezing of gait score
Time Frame: One week
The primary outcome is the freezing of gait score. 12-item scale, each item scores 3 points at maximum; the score ranges from 0-36; higher scores mean higher severity
Secondary Outcomes
- Gait speed(baseline, 1 week, 4 week)
- Freezing of gait questionnaire(baseline, 1 week, 4 week)
- Safety of the intervention - urinary incontinence(1 week, 4 week)
- Safety of the intervention - lower limb strength.(1 week, 4 week)